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Introduction

Selenium is an essential trace element that plays a crucial role in human health. It is involved in numerous physiological processes, including antioxidant defense, thyroid hormone metabolism, and immune function. Selenium deficiency has been linked to a variety of health problems, such as cardiovascular disease, cancer, and cognitive decline. On the other hand, excessive selenium intake can also have detrimental effects on health. Therefore, understanding the role of selenium in health is of utmost importance for public health and clinical practice.

Chapter 1: Introduction

1.1 Introduction
1.2 Background of study
1.3 Problem Statement
1.4 Objective of study
1.5 Limitation of study
1.6 Scope of study
1.7 Significance of study
1.8 Structure of the Thesis
1.9 Definition of terms

Chapter 2: Literature Review

2.1 Historical perspective of selenium research
2.2 Biochemical functions of selenium
2.3 Sources of selenium in the diet
2.4 Selenium deficiency and toxicity
2.5 Selenium and cardiovascular health
2.6 Selenium and cancer
2.7 Selenium and immune function
2.8 Selenium and cognitive health
2.9 Selenium supplementation
2.10 Current recommendations for selenium intake

Chapter 3: Research Methodology

3.1 Research design
3.2 Study population
3.3 Data collection methods
3.4 Data analysis
3.5 Ethical considerations
3.6 Validity and reliability
3.7 Sampling technique
3.8 Statistical analysis

Chapter 4: Discussion of Findings

4.1 Relationship between selenium intake and health outcomes
4.2 Factors influencing selenium status
4.3 Public health implications of selenium deficiency
4.4 Clinical implications of selenium supplementation
4.5 Future research directions
4.6 Comparison with existing literature
4.7 Potential limitations of the study
4.8 Recommendations for further research

Chapter 5: Conclusion

In conclusion, the role of selenium in health is multifaceted and complex. This thesis has provided a comprehensive overview of the current state of knowledge on selenium and its impact on human health. It is hoped that this research will contribute to a better understanding of the importance of selenium in maintaining optimal health and inform future public health policies and clinical practices.

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