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Introduction:
Neurodegenerative diseases are a group of disorders characterized by the progressive degeneration of the structure and function of the nervous system. These diseases, such as Alzheimer’s disease, Parkinson’s disease, and multiple sclerosis, have devastating effects on individuals, their families, and society as a whole. Microglia, the resident immune cells of the central nervous system, have emerged as key players in the pathogenesis of neurodegenerative diseases. Understanding the intricate role of microglia in these disorders is crucial for the development of effective therapeutic strategies. This thesis aims to explore the role of microglia in neurodegenerative diseases and provide new insights into potential treatment approaches.

Table of Contents:
1.1 Introduction
1.2 Background of Study
1.3 Problem Statement
1.4 Objective of Study
1.5 Limitation of Study
1.6 Scope of Study
1.7 Significance of Study
1.8 Structure of the Thesis
1.9 Definition of Terms

Chapter Two: Literature Review
– Overview of Neurodegenerative Diseases
– Role of Microglia in the Central Nervous System
– Interaction Between Microglia and Neurons
– Inflammatory Responses in Neurodegenerative Diseases
– Neuroprotective Functions of Microglia
– Dysregulation of Microglia in Disease Pathogenesis
– Therapeutic Targeting of Microglia
– Current Research Trends in Microglia and Neurodegenerative Diseases
– Challenges and Future Perspectives
– Summary of Literature Review

Chapter Three: Research Methodology
– Research Design
– Sampling Technique
– Data Collection Methods
– Data Analysis Techniques
– Ethical Considerations
– Research Limitations
– Reliability and Validity
– Research Timeline

Chapter Four: Discussion of Findings
– Analysis of Study Results
– Comparison with Existing Literature
– Implications for Clinical Practice
– Recommendations for Future Research
– Limitations of the Study
– Strengths of the Study

Chapter Five: Conclusion and Summary
– Recap of Research Objectives
– Summary of Key Findings
– Clinical Implications
– Recommendations for Practice
– Concluding Remarks

Thesis Overview:
The role of microglia in neurodegenerative diseases has been a topic of intense research in recent years. This thesis aims to provide a comprehensive overview of the current understanding of how microglia contribute to the pathogenesis of neurodegenerative diseases and explore potential therapeutic strategies targeting these immune cells. The literature review will examine the latest findings on the role of microglia in the central nervous system, their interactions with neurons, and their dysregulation in neurodegenerative diseases. The research methodology section will detail the study design, data collection methods, and ethical considerations. The discussion of findings will analyze the results of the study, compare them with existing literature, and provide recommendations for future research. The conclusion will summarize the key findings, discuss their clinical implications, and suggest directions for further investigation in this important field of study.

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