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Introduction

The pharmacovigilance system plays a crucial role in monitoring the safety and effectiveness of pharmaceutical products after they have been approved for marketing. Despite significant advancements in pharmacovigilance practices, there are still gaps in surveillance that need to be addressed to ensure the timely detection and management of adverse drug reactions. This thesis aims to explore these gaps and propose improvements to enhance the effectiveness of the pharmacovigilance system.

Chapter 1: Introduction
1.1 Introduction
1.2 Background of study
1.3 Problem Statement
1.4 Objective of study
1.5 Limitation of study
1.6 Scope of study
1.7 Significance of study
1.8 Structure of the Thesis
1.9 Definition of terms

Chapter 2: Literature Review
2.1 Overview of pharmacovigilance system
2.2 Current challenges in pharmacovigilance surveillance
2.3 Importance of pharmacovigilance in public health
2.4 Global pharmacovigilance regulations and guidelines
2.5 Role of healthcare professionals in pharmacovigilance reporting
2.6 Patient involvement in pharmacovigilance
2.7 Use of technology in pharmacovigilance
2.8 Pharmacovigilance in developing countries
2.9 Pharmacovigilance in special populations
2.10 Future directions in pharmacovigilance research

Chapter 3: Research Methodology
3.1 Research design
3.2 Data collection methods
3.3 Data analysis techniques
3.4 Study population
3.5 Sampling strategy
3.6 Ethical considerations
3.7 Validity and reliability
3.8 Limitations of the study

Chapter 4: Discussion of Findings
4.1 Overview of findings
4.2 Analysis of surveillance gaps
4.3 Proposed improvements in pharmacovigilance system
4.4 Implementation strategies
4.5 Stakeholder involvement
4.6 Challenges and barriers
4.7 Recommendations for future research
4.8 Implications for practice

Chapter 5: Conclusion and Summary
5.1 Summary of key findings
5.2 Contribution to the field of pharmacovigilance
5.3 Practical implications
5.4 Recommendations for policymakers
5.5 Areas for future research

Thesis Overview

The pharmacovigilance system is a critical component of public health that monitors the safety and effectiveness of pharmaceutical products. Despite its importance, there are still gaps in surveillance that need to be addressed to ensure the timely detection and management of adverse drug reactions. This thesis aims to identify these gaps and propose improvements to enhance the effectiveness of the pharmacovigilance system.

Chapter 1 provides an introduction to the topic, outlining the background of the study, the problem statement, objectives, limitations, scope, significance, structure of the thesis, and definition of terms. Chapter 2 presents a comprehensive literature review on the pharmacovigilance system, highlighting current challenges, global regulations, stakeholder roles, and future directions in research.

Chapter 3 details the research methodology, including design, data collection methods, analysis techniques, study population, sampling strategy, ethical considerations, validity, reliability, and limitations. Chapter 4 discusses the findings of the study, analyzing surveillance gaps, proposing improvements, discussing implementation strategies, stakeholder involvement, challenges, recommendations, and implications for practice.

Chapter 5 concludes the thesis, summarizing key findings, contributions to the field, practical implications, recommendations for policymakers, and areas for future research. Overall, this thesis aims to contribute to the ongoing efforts to enhance pharmacovigilance practices and ensure the safety of pharmaceutical products for all individuals.

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