[ad_1] Introduction Receptor tyrosine kinases (RTKs) play a crucial role in cellular signaling pathways and are involved in various physiological and pathological processes, including cancer and fibrosis. Dysregulation of RTK signaling has been implicated in…
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[ad_1] Introduction In recent years, microdosing has emerged as a promising strategy in early drug development. Microdosing involves the administration of sub-therapeutic doses of a drug to human subjects in order to study its pharmacokinetics…
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[ad_1] Introduction Distribution and elimination sites play a crucial role in the pharmacokinetics and pharmacodynamics of drugs. Understanding the processes involved in distribution and elimination is essential for optimizing drug therapy and minimizing adverse effects.…
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[ad_1] Introduction Bioavailability refers to the proportion of a drug or other substance that enters the bloodstream when introduced into the body and is able to have an active effect. Enhancing the bioavailability of molecules…
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[ad_1] Introduction Neurodegeneration and fibrosis are two pathologies that have gained increasing attention in the field of medical research due to their significant impact on human health. Neurodegeneration refers to the progressive loss of structure…
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[ad_1] Introduction Cancer is a leading cause of death worldwide, with millions of individuals diagnosed each year. Despite advancements in treatments, many cancer patients still face poor outcomes due to resistance to conventional therapies. MicroRNAs…
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[ad_1] Introduction Monoclonal antibodies have revolutionized the treatment of various diseases, including cancer, autoimmune disorders, and infectious diseases. These antibodies are designed to specifically target and bind to antigens, leading to therapeutic effects. Understanding the…
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[ad_1] Introduction: Anti-infective drugs play a crucial role in the treatment of infectious diseases, which remain a significant global health challenge. The emergence of antimicrobial resistance has become a major concern in recent years, leading…
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[ad_1] Introduction Biopharmaceutics and pharmacokinetics play a crucial role in determining the efficacy and safety of drug delivery formulations. The development of oral lipid-based drug delivery formulations has gained significant attention in recent years due…
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[ad_1] Introduction: Computational methods in structure-based drug design have revolutionized the field of pharmacology by providing a more efficient and cost-effective approach to drug discovery. This is particularly important for G protein-coupled receptors (GPCRs), which…
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