[ad_1] Introduction: Exosomes are small extracellular vesicles that play a crucial role in cell-to-cell communication by transferring bioactive molecules such as proteins, lipids, and nucleic acids. In recent years, exosomes have gained significant attention as…
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[ad_1] Introduction: The prevalence of metabolic syndrome and nonalcoholic fatty liver disease (NAFLD) has been steadily increasing worldwide, posing a significant public health concern. These metabolic disorders are closely linked and share common underlying pathophysiological…
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[ad_1] Introduction Functional genomics has revolutionized the field of pharmacology by providing valuable insights into the identification of targets and pathways for drug discovery and development. Understanding the complex interactions between genes, proteins, and pathways…
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[ad_1] Introduction Biomarkers are measurable substances or indicators that can be used to assess biological processes, disease progression, or responses to treatment. In the field of safety, biomarkers play a crucial role in identifying potential…
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[ad_1] Introduction: The field of pharmacology has made tremendous advancements in recent years, owing to the development and application of computational tools in systems pharmacology and polypharmacology. These tools have enabled researchers to understand the…
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[ad_1] Introduction The discovery of new drugs is a complex and multifaceted process that requires a deep understanding of both the biological targets and the chemical compounds that interact with them. In recent years, there…
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[ad_1] Introduction In recent years, there has been a growing concern regarding the potential side effects of pharmaceutical drugs on bone and cartilage health. Drug-induced osteotoxicity and cartilage damage can have severe consequences for patients,…
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[ad_1] Introduction In recent years, microdosing has emerged as a promising strategy in early drug development. Microdosing involves the administration of sub-therapeutic doses of a drug to human subjects in order to study its pharmacokinetics…
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[ad_1] Introduction Distribution and elimination sites play a crucial role in the pharmacokinetics and pharmacodynamics of drugs. Understanding the processes involved in distribution and elimination is essential for optimizing drug therapy and minimizing adverse effects.…
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[ad_1] Introduction Bioavailability refers to the proportion of a drug or other substance that enters the bloodstream when introduced into the body and is able to have an active effect. Enhancing the bioavailability of molecules…
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