[ad_1] Introduction Cellular signaling is a complex process that allows cells to communicate with each other and respond to their environment. One important class of signaling molecules are G-protein coupled receptors (GPCRs), which are involved…
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[ad_1] Introduction Transdermal drug delivery using microneedles and nanocarriers has emerged as a promising method for enhancing drug delivery efficiency, reducing side effects, and improving patient compliance. This innovative approach involves the use of microneedles…
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[ad_1] Introduction Structure-activity relationships (SAR) play a crucial role in the field of drug design, as they provide important insights into how the chemical structure of a molecule influences its biological activity. By studying the…
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[ad_1] Introduction Drug transporters play a crucial role in the pharmacokinetics of drugs by facilitating the movement of drugs across cell membranes. These transporters are essential for the absorption, distribution, metabolism, and excretion of drugs…
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[ad_1] Introduction Drug resistance is a major challenge in cancer chemotherapy, leading to treatment failure and disease recurrence. Understanding the molecular mechanisms underlying drug resistance is crucial for developing effective strategies to overcome this obstacle…
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[ad_1] Thesis Overview: Pharmacokinetics is the study of how drugs are absorbed, distributed, metabolized, and excreted by the body. Understanding these processes is essential for determining the appropriate dosage of a drug and predicting its…
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[ad_1] Introduction Drug target identification and validation are crucial steps in drug discovery and development processes. Omics approaches, including genomics, transcriptomics, proteomics, and metabolomics, have revolutionized the field by enabling the comprehensive analysis of biological…
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[ad_1] Introduction Polycystic kidney disease (PKD) is a genetic disorder characterized by the growth of numerous cysts in the kidneys, leading to kidney enlargement and eventual kidney failure. It is one of the most common…
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[ad_1] Introduction Friedreichʼs ataxia is a rare progressive genetic disorder that affects coordination, balance, and muscle control. Currently, there is no cure for this debilitating disease, and treatment options are limited. However, recent advancements in…
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[ad_1] Thesis Overview: Systemic sclerosis is a chronic autoimmune disease characterized by excessive collagen production leading to fibrosis of the skin and internal organs. Currently, treatment options for systemic sclerosis are limited, and there is…
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