[ad_1] Introduction In recent years, there has been a growing recognition of the need for a more comprehensive approach to drug development in pediatric populations. Physiologically based pharmacokinetic (PBPK) models have emerged as a valuable…
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[ad_1] Introduction Functional genomics has revolutionized the field of pharmacology by providing valuable insights into the identification of targets and pathways for drug discovery and development. Understanding the complex interactions between genes, proteins, and pathways…
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[ad_1] Introduction: Advanced bioanalytical techniques play a crucial role in pharmacokinetic studies and metabolism characterization, providing valuable insights into the absorption, distribution, metabolism, and excretion of drugs in the body. These techniques have revolutionized the…
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[ad_1] Introduction Drug efficacy and mechanisms of action are critical aspects of pharmacology and are essential for understanding the effects of drugs on the human body. The efficacy of a drug refers to its ability…
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[ad_1] In recent years, drug delivery technologies for ocular disorders have become increasingly important as advances in medicine have allowed for more targeted and efficient treatments. The eye is a complex and unique organ with…
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[ad_1] Introduction Pharmacogenomics is a rapidly evolving field that aims to personalize medicine by studying how an individual’s genetic makeup influences their response to drugs. Drug-drug interactions and adverse events are common challenges in clinical…
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[ad_1] Introduction In recent years, there has been a growing concern regarding the potential side effects of pharmaceutical drugs on bone and cartilage health. Drug-induced osteotoxicity and cartilage damage can have severe consequences for patients,…
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[ad_1] Introduction In recent years, microdosing has emerged as a promising strategy in early drug development. Microdosing involves the administration of sub-therapeutic doses of a drug to human subjects in order to study its pharmacokinetics…
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[ad_1] Introduction: Pharmacogenetics is a branch of pharmacology that studies the role of genetic variation in drug response. Adverse drug reactions (ADRs) are a major concern in healthcare as they can lead to serious health…
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[ad_1] Introduction Drug-tissue interactions at absorption play a crucial role in determining the pharmacokinetics and pharmacodynamics of drugs in the body. Understanding how drugs interact with various tissues during the absorption process is essential for…
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