[ad_1] Introduction Membrane transporters play a crucial role in drug resistance, a major challenge in the treatment of various diseases such as cancer and infectious diseases. Drug resistance occurs when cells develop mechanisms to evade…
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[ad_1] Introduction Cell penetrating peptides (CPPs) have attracted significant attention in recent years due to their ability to efficiently deliver various cargoes, including drugs and genes, across biological membranes. CPPs are short peptides that possess…
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[ad_1] Introduction Neuropsychiatric conditions, which encompass a range of disorders affecting the brain and nervous system, are a significant public health concern worldwide. These conditions, including but not limited to depression, anxiety, schizophrenia, and bipolar…
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[ad_1] Introduction G protein-coupled receptors (GPCRs) are crucial players in signal transduction, regulating a wide variety of physiological processes. Recent studies have shown that GPCRs can form oligomeric complexes, which can influence their function and…
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[ad_1] Introduction: The prevalence of metabolic syndrome and nonalcoholic fatty liver disease (NAFLD) has been steadily increasing worldwide, posing a significant public health concern. These metabolic disorders are closely linked and share common underlying pathophysiological…
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[ad_1] Introduction In recent years, there has been a growing recognition of the need for a more comprehensive approach to drug development in pediatric populations. Physiologically based pharmacokinetic (PBPK) models have emerged as a valuable…
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[ad_1] Introduction: The field of pharmacology has made tremendous advancements in recent years, owing to the development and application of computational tools in systems pharmacology and polypharmacology. These tools have enabled researchers to understand the…
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[ad_1] In recent years, drug delivery technologies for ocular disorders have become increasingly important as advances in medicine have allowed for more targeted and efficient treatments. The eye is a complex and unique organ with…
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[ad_1] Introduction Pharmacogenomics is a rapidly evolving field that aims to personalize medicine by studying how an individual’s genetic makeup influences their response to drugs. Drug-drug interactions and adverse events are common challenges in clinical…
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[ad_1] Introduction The discovery of new drugs is a complex and multifaceted process that requires a deep understanding of both the biological targets and the chemical compounds that interact with them. In recent years, there…
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