[ad_1] Introduction Bacterial toxins play a significant role in the pathogenicity of many bacterial species, allowing them to evade host immune responses and cause disease. Understanding the structural biology of these toxins is crucial for…
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[ad_1] Introduction Proteins play crucial roles in various biological processes and are often targeted by inhibitors in drug development efforts. Understanding the structural details of protein-inhibitor complexes is important for designing more effective and specific…
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[ad_1] Introduction Metabolic reprogramming plays a crucial role in the pathophysiology of acute liver failure (ALF). ALF is a life-threatening condition characterized by sudden and severe liver dysfunction, which can lead to multiple organ failure…
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[ad_1] Introduction Heat shock proteins (HSPs) are a group of highly conserved proteins that are responsible for maintaining cellular homeostasis under stress conditions. They play a crucial role in protein folding, trafficking, and degradation, as…
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[ad_1] Introduction Proteomics is a rapidly evolving field that plays a crucial role in understanding the pathophysiology of various diseases by identifying and quantifying proteins expressed in biological samples. Peritoneal fluid, also known as ascites,…
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[ad_1] Introduction The aqueous humor is a clear fluid that fills the anterior chamber of the eye, providing essential nutrients to the avascular tissues of the cornea and lens. The dynamics of aqueous humor, including…
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[ad_1] Introduction Drug-induced skin reactions are a common and potentially serious side effect of many medications. These reactions can range from mild rashes to severe blistering and skin necrosis, and can have a significant impact…
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[ad_1] Introduction Protein palmitoylation is a post-translational modification process that involves the addition of a saturated 16-carbon palmitoyl group to specific cysteine residues of proteins. This reversible modification plays a crucial role in regulating protein…
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[ad_1] Introduction Acute kidney injury (AKI) is a common and potentially life-threatening condition characterized by a sudden loss of kidney function. The pathophysiology of AKI involves complex molecular mechanisms, including metabolic reprogramming. Metabolic reprogramming refers…
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[ad_1] Introduction Reproductive toxicity is a major concern in drug development and pharmacovigilance as it can have serious implications on human health and fertility. Drug-induced reproductive toxicity refers to the adverse effects of pharmaceutical compounds…
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