[ad_1] Introduction Rare metabolic disorders are a group of genetic diseases characterized by defects in metabolic pathways, leading to a wide range of symptoms and complications. These disorders often have limited treatment options, with few…
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[ad_1] Introduction Metabolic reprogramming is a pivotal mechanism through which cells adapt to their microenvironment and support rapid proliferation in various disease states, including cancer and metabolic disorders. The manipulation of metabolic pathways through pharmacological…
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[ad_1] Introduction In recent years, immunotherapy has emerged as a promising approach for cancer treatment. However, the success of immunotherapy is highly dependent on the effective delivery of therapeutic agents to target sites within the…
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[ad_1] Introduction: Drug-induced hypophosphatemia is a condition characterized by low levels of phosphate in the blood caused by the use of certain medications. Phosphate is an essential mineral that plays a crucial role in various…
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[ad_1] Introduction: Prurigo nodularis is a chronic skin condition characterized by the presence of pruritic nodules on the skin. It is a challenging condition to treat, as traditional therapies often provide limited relief for patients.…
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[ad_1] Introduction Drug repurposing, also known as drug repositioning or drug reprofiling, is the process of discovering new therapeutic uses for existing drugs. This strategy has gained significant attention in recent years due to its…
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[ad_1] Introduction Alternative splicing is a crucial mechanism that allows a single gene to code for multiple protein variants. This process, regulated by splicing factors, is essential for cellular function and development. Dysregulation of alternative…
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[ad_1] Introduction Drug-induced toxic epidermal necrolysis (TEN) is a severe and potentially life-threatening skin reaction that is often caused by a reaction to medications. TEN is characterized by the detachment of the skin and mucous…
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[ad_1] Introduction Preeclampsia is a pregnancy-related disorder characterized by hypertension and proteinuria, with serious implications for both the mother and the developing fetus. It is a leading cause of maternal and neonatal morbidity and mortality…
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[ad_1] Introduction Drug discovery from permafrost microorganisms is an emerging field of research with significant potential for discovering novel bioactive compounds with therapeutic properties. Permafrost, which consists of permanently frozen soil and rock, has long…
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