[ad_1] Introduction Protein-drug complexes play a crucial role in understanding the interactions between drugs and their target proteins. Structural studies of protein-drug complexes provide valuable insights into the mechanisms of drug action, drug design, and…
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[ad_1] Introduction: Septic shock is a life-threatening condition that arises from a dysregulated host response to infection, leading to widespread inflammation, tissue damage, and organ dysfunction. Metabolic reprogramming has emerged as a key mechanism underlying…
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[ad_1] Introduction Nitric oxide (NO) is a vital signaling molecule involved in various physiological and pathological processes in the human body. Since its discovery as a biological signaling molecule in the 1980s, extensive research has…
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[ad_1] Introduction Viral fusion proteins are essential components of viruses that facilitate the entry of viral genetic material into host cells. Understanding the structural biology of viral fusion proteins is crucial in developing antiviral therapies…
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[ad_1] Introduction Huntington’s disease (HD) is a devastating neurodegenerative disorder characterized by progressive motor dysfunction, cognitive decline, and psychiatric symptoms. Despite significant advances in understanding the genetic basis of HD, there is still a need…
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[ad_1] Introduction Protein ADP-ribosylation is a post-translational modification process that plays a crucial role in various cellular functions such as DNA repair, cell signaling, and gene expression. The attachment of ADP-ribose moieties to proteins is…
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[ad_1] Introduction Periodontal diseases are inflammatory conditions that affect the supporting structures of the teeth, including the gingiva, periodontal ligament, and alveolar bone. Gingival crevicular fluid (GCF) is a fluid that flows from the gingival…
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[ad_1] Introduction: Proteins play a crucial role in many biological processes, serving as enzymes, receptors, transporters, and structural components in cells. Understanding the structural details of protein-substrate complexes is essential for designing drugs, modifying enzymes,…
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[ad_1] Introduction Thyroid toxicity induced by drugs is a significant issue in the field of pharmacology and endocrinology. The thyroid gland plays a crucial role in regulating metabolism, growth, and development in the human body.…
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[ad_1] Introduction: Protein-DNA interactions play a crucial role in DNA replication, as proteins are responsible for unwinding the DNA helix, synthesizing new DNA strands, and ensuring accurate duplication of genetic material. Understanding the intricate interplay…
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