[ad_1] Introduction Drug transporters at the blood-CSF barrier play a crucial role in regulating the passage of therapeutic agents from the systemic circulation into the central nervous system (CNS). Understanding the mechanisms by which these…
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[ad_1] Introduction Neurodegeneration and fibrosis are two pathologies that have gained increasing attention in the field of medical research due to their significant impact on human health. Neurodegeneration refers to the progressive loss of structure…
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[ad_1] Introduction Cancer is a leading cause of death worldwide, with millions of individuals diagnosed each year. Despite advancements in treatments, many cancer patients still face poor outcomes due to resistance to conventional therapies. MicroRNAs…
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[ad_1] Introduction: Anti-infective drugs play a crucial role in the treatment of infectious diseases, which remain a significant global health challenge. The emergence of antimicrobial resistance has become a major concern in recent years, leading…
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[ad_1] Introduction Biopharmaceutics and pharmacokinetics play a crucial role in determining the efficacy and safety of drug delivery formulations. The development of oral lipid-based drug delivery formulations has gained significant attention in recent years due…
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[ad_1] Introduction: Computational methods in structure-based drug design have revolutionized the field of pharmacology by providing a more efficient and cost-effective approach to drug discovery. This is particularly important for G protein-coupled receptors (GPCRs), which…
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[ad_1] Introduction Pharmacology of voltage gated calcium channels (VGCCs) has gained significant attention in the field of drug development due to their crucial role in a variety of physiological processes. VGCCs are essential for the…
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[ad_1] Introduction Protein misfolding diseases are a group of disorders characterized by the accumulation of misfolded proteins in cells and tissues, leading to cell dysfunction and tissue damage. These diseases include neurodegenerative disorders such as…
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[ad_1] Introduction: Ion channels play a crucial role in the regulation of cellular functions, including the maintenance of electrical signals in excitable cells such as neurons and cardiomyocytes. Dysregulation of ion channels has been implicated…
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[ad_1] Introduction: Parasitic infections remain a major global health concern, affecting millions of people worldwide, particularly in developing countries. The development of effective anti-parasitic drugs is crucial in the fight against these infections, as drug…
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