Introduction Protein farnesylation is a post-translational modification process that involves the addition of a farnesyl isoprenoid lipid group to specific proteins. This modification plays a crucial role in regulating various cellular processes such as signal…
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Introduction Proteomics is a rapidly evolving field that plays a crucial role in understanding the pathophysiology of various diseases by identifying and quantifying proteins expressed in biological samples. Peritoneal fluid, also known as ascites, is…
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Introduction: Marathons are long-distance running events that require a high level of endurance and physical fitness. Marathon runners undergo rigorous training and dietary regimes to improve their performance. One key aspect of marathon running is…
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Introduction Protein-carbohydrate interactions play a crucial role in bacterial adhesion, a key step in the initiation of bacterial infections. Understanding the mechanisms behind these interactions is essential for the development of therapeutic strategies to prevent…
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Introduction Melanocytes are melanin-producing cells that play a crucial role in determining the pigmentation of the skin, hair, and eyes. The biochemistry of melanocyte function is a complex and intricate process that involves the synthesis,…
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Introduction Metabolomics is a powerful tool used to study the biochemical processes in living organisms, providing valuable insights into disease mechanisms and potential therapeutic targets. Parkinsonʼs disease (PD) is a progressive neurodegenerative disorder that affects…
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Introduction Proteomics of exhaled breath condensate has emerged as a non-invasive and promising approach for the diagnosis and monitoring of lung diseases. This thesis aims to investigate the potential of proteomic analysis of exhaled breath…
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Introduction Acute kidney injury (AKI) is a common and potentially life-threatening condition characterized by a sudden loss of kidney function. The pathophysiology of AKI involves complex molecular mechanisms, including metabolic reprogramming. Metabolic reprogramming refers to…
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Introduction Reproductive toxicity is a major concern in drug development and pharmacovigilance as it can have serious implications on human health and fertility. Drug-induced reproductive toxicity refers to the adverse effects of pharmaceutical compounds on…
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Introduction Melatonin is a hormone that is primarily produced by the pineal gland in the brain and is involved in the regulation of the sleep-wake cycle. It is known for its antioxidant properties and its…
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