[ad_1] Introduction: Proteins play a crucial role in many biological processes, serving as enzymes, receptors, transporters, and structural components in cells. Understanding the structural details of protein-substrate complexes is essential for designing drugs, modifying enzymes,…
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[ad_1] Introduction Thyroid toxicity induced by drugs is a significant issue in the field of pharmacology and endocrinology. The thyroid gland plays a crucial role in regulating metabolism, growth, and development in the human body.…
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[ad_1] Introduction Bacterial toxins play a significant role in the pathogenicity of many bacterial species, allowing them to evade host immune responses and cause disease. Understanding the structural biology of these toxins is crucial for…
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[ad_1] Introduction Protein prenylation is a post-translational modification that involves the addition of lipid groups, such as farnesyl or geranylgeranyl moieties, to specific cysteine residues near the C-terminus of proteins. This modification plays a crucial…
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[ad_1] Introduction Proteins play crucial roles in various biological processes and are often targeted by inhibitors in drug development efforts. Understanding the structural details of protein-inhibitor complexes is important for designing more effective and specific…
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[ad_1] Introduction Metabolic reprogramming plays a crucial role in the pathophysiology of acute liver failure (ALF). ALF is a life-threatening condition characterized by sudden and severe liver dysfunction, which can lead to multiple organ failure…
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[ad_1] Introduction: Drug-induced pulmonary toxicity is a serious and potentially life-threatening side effect of many medications. Understanding the biochemical basis of this toxicity is crucial for the development of safer drugs and more effective treatment…
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[ad_1] Introduction The process of neurotransmitter reuptake plays a crucial role in the regulation of neurotransmission within the central nervous system. Neurotransmitters are chemical messengers that transmit signals between neurons, allowing for the communication and…
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[ad_1] Introduction Heat shock proteins (HSPs) are a group of highly conserved proteins that are responsible for maintaining cellular homeostasis under stress conditions. They play a crucial role in protein folding, trafficking, and degradation, as…
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[ad_1] Introduction Protein farnesylation is a post-translational modification process that involves the addition of a farnesyl isoprenoid lipid group to specific proteins. This modification plays a crucial role in regulating various cellular processes such as…
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