[ad_1] Introduction Reactive oxygen species (ROS) are highly reactive oxygen-containing molecules that play a dual role in cells, acting both as signaling molecules and as harmful agents causing oxidative damage. The balance between ROS production…
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[ad_1] Introduction Structure-guided drug design using protein crystallography is a powerful approach in drug discovery that involves the determination of the three-dimensional structures of proteins involved in disease processes. This method allows researchers to design…
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[ad_1] Introduction Autophagy is a fundamental cellular process that involves the degradation and recycling of cellular components to maintain cellular homeostasis. This process plays a crucial role in various physiological and pathological conditions, including cancer,…
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[ad_1] Introduction Enzymes are biological catalysts that play a crucial role in accelerating chemical reactions within living organisms. The evolution of enzymes and their catalytic mechanisms are of great interest to scientists as they provide…
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[ad_1] Introduction Computational modeling of G-protein coupled receptor (GPCR) signaling is a growing field within the realm of molecular biology and pharmacology. GPCRs are a large family of cell surface receptors that play key roles…
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[ad_1] Introduction: Obesity and diabetes are two major health issues that have reached epidemic proportions globally. Both conditions are closely linked to disruptions in carbohydrate and lipid metabolism, which play a crucial role in the…
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[ad_1] Introduction: Prion diseases, also known as transmissible spongiform encephalopathies (TSEs), are a group of rare and fatal neurodegenerative disorders that affect both humans and animals. These diseases are characterized by the accumulation of misfolded…
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[ad_1] Introduction Metabolomics is a powerful approach for discovering biomarkers that can provide valuable insights into the physiological and pathological processes occurring within an organism. The identification of biomarkers is crucial for early disease detection,…
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[ad_1] Introduction Protein structure prediction is a crucial field in bioinformatics that involves predicting the three-dimensional structure of a protein based on its amino acid sequence. Understanding protein structure is essential for drug design, disease…
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[ad_1] Introduction Dynamics and allostery play crucial roles in the regulation of proteins, particularly in the context of cellular signaling pathways. Regulatory proteins are essential for the proper functioning of biological systems, as they control…
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