[ad_1] Introduction Receptor tyrosine kinases (RTKs) play a crucial role in cellular signaling pathways and are involved in various physiological and pathological processes, including cancer and fibrosis. Dysregulation of RTK signaling has been implicated in…
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[ad_1] Introduction In recent years, microdosing has emerged as a promising strategy in early drug development. Microdosing involves the administration of sub-therapeutic doses of a drug to human subjects in order to study its pharmacokinetics…
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[ad_1] Introduction: Pharmacogenetics is a branch of pharmacology that studies the role of genetic variation in drug response. Adverse drug reactions (ADRs) are a major concern in healthcare as they can lead to serious health…
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[ad_1] Introduction Bioavailability refers to the proportion of a drug or other substance that enters the bloodstream when introduced into the body and is able to have an active effect. Enhancing the bioavailability of molecules…
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[ad_1] Introduction Drug transporters at the blood-CSF barrier play a crucial role in regulating the passage of therapeutic agents from the systemic circulation into the central nervous system (CNS). Understanding the mechanisms by which these…
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[ad_1] Introduction Neurodegeneration and fibrosis are two pathologies that have gained increasing attention in the field of medical research due to their significant impact on human health. Neurodegeneration refers to the progressive loss of structure…
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[ad_1] Introduction Microfluidics-based screening tools have emerged as a powerful technology for studying drug metabolism and interactions in recent years. These tools offer several advantages over traditional methods, including the ability to perform high-throughput experiments…
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[ad_1] Introduction: Anti-infective drugs play a crucial role in the treatment of infectious diseases, which remain a significant global health challenge. The emergence of antimicrobial resistance has become a major concern in recent years, leading…
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[ad_1] Introduction Biopharmaceutics and pharmacokinetics play a crucial role in determining the efficacy and safety of drug delivery formulations. The development of oral lipid-based drug delivery formulations has gained significant attention in recent years due…
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[ad_1] Introduction: Computational methods in structure-based drug design have revolutionized the field of pharmacology by providing a more efficient and cost-effective approach to drug discovery. This is particularly important for G protein-coupled receptors (GPCRs), which…
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