Introduction Bacterial autotransporters are a family of proteins found in Gram-negative bacteria that play a crucial role in the transport of virulence factors across the bacterial cell membrane. These proteins are involved in a wide…
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Introduction Anorexia nervosa is a complex psychiatric disorder characterized by restricted food intake, intense fear of gaining weight, and distorted body image. Despite advances in understanding the etiology and treatment of anorexia nervosa, the underlying…
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Introduction Protein glutathionylation is a critical post-translational modification that plays a significant role in the regulation of cellular redox balance and signaling pathways. Glutathionylation involves the formation of a disulfide bond between glutathione and a…
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Introduction: Drug-induced hepatotoxicity is a serious and potentially life-threatening adverse effect of many medications. Hepatotoxicity refers to damage of the liver caused by various chemical substances, including drugs. The biochemical basis of drug-induced hepatotoxicity is…
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Introduction Bacterial adhesins are surface proteins that play a crucial role in the interaction between bacteria and their host cells. Understanding the structural biology of bacterial adhesins is essential for developing strategies to combat bacterial…
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Introduction Obsessive-Compulsive Disorder (OCD) is a chronic mental disorder characterized by intrusive thoughts (obsessions) and repetitive behaviors (compulsions) that cause significant distress and impairment in daily functioning. While the exact etiology of OCD remains unknown,…
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Introduction The glymphatic system is a recently discovered waste clearance pathway in the brain that plays a crucial role in maintaining brain health and function. This system is responsible for removing toxic waste products, including…
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Introduction Drug-induced nephrotoxicity is a significant clinical problem that can lead to acute kidney injury, chronic kidney disease, and even end-stage renal disease. It is a common cause of drug-related morbidity and mortality, particularly in…
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Introduction: Protein-RNA interactions play a crucial role in stress granule formation, a cellular response to various stress conditions such as heat shock, oxidative stress, and viral infection. Stress granules are dynamic, membraneless organelles that serve…
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