Predicting patient mortality using clinical data and machine learning – Complete Phd and Masters Thesis

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Introduction

The use of machine learning in healthcare has been gaining popularity in recent years, with researchers and clinicians exploring its potential applications in predicting patient outcomes. One such application is predicting patient mortality using clinical data and machine learning algorithms. By leveraging the vast amounts of data available in electronic health records, researchers can develop predictive models that can help healthcare providers identify high-risk patients and intervene early to prevent adverse outcomes.

This thesis aims to explore the use of machine learning techniques in predicting patient mortality using clinical data. The research will focus on developing and evaluating predictive models that can accurately identify patients at risk of mortality based on their clinical characteristics. By doing so, this research seeks to improve patient outcomes and reduce healthcare costs by enabling proactive and targeted interventions for high-risk patients.

Chapter 1: Introduction
1.1 Introduction
1.2 Background of study
1.3 Problem Statement
1.4 Objective of study
1.5 Limitation of study
1.6 Scope of study
1.7 Significance of study
1.8 Structure of the Thesis
1.9 Definition of Terms

Chapter 2: Literature Review
2.1 Overview of machine learning in healthcare
2.2 Predictive modeling in healthcare
2.3 Previous studies on predicting patient mortality
2.4 Use of clinical data in predictive modeling
2.5 Challenges in predicting patient mortality
2.6 Ethical considerations in predictive modeling
2.7 Current state of the art in machine learning for predicting patient outcomes
2.8 Comparison of different machine learning algorithms
2.9 Interpretability and explainability in predictive modeling
2.10 Future directions in predicting patient mortality using clinical data and machine learning

Chapter 3: Research Methodology
3.1 Research design
3.2 Data collection and preprocessing
3.3 Feature selection and engineering
3.4 Model development
3.5 Model evaluation
3.6 Performance metrics
3.7 Cross-validation and hyperparameter tuning
3.8 Ethical considerations
3.9 Statistical analysis
3.10 Software tools and programming languages

Chapter 4: Discussion of Findings
4.1 Performance of predictive models
4.2 Factors influencing model performance
4.3 Clinical relevance of predictive features
4.4 Comparison with existing models
4.5 Limitations of the study
4.6 Implications for clinical practice
4.7 Recommendations for future research

Chapter 5: Conclusion and Summary
5.1 Summary of findings
5.2 Contributions to the field
5.3 Practical implications
5.4 Limitations of the study
5.5 Future research directions
5.6 Conclusion

Thesis Overview

The use of machine learning in healthcare has opened up new possibilities for predicting patient outcomes based on clinical data. In this thesis, we focus on predicting patient mortality using machine learning algorithms and clinical data from electronic health records. By developing predictive models that can identify high-risk patients, healthcare providers can intervene early and improve patient outcomes.

Chapter 1 provides an introduction to the research topic, including the background, problem statement, objectives, limitations, scope, significance, structure of the thesis, and definition of key terms. Chapter 2 presents a comprehensive literature review on machine learning in healthcare, predictive modeling, previous studies on predicting patient mortality, challenges, ethical considerations, current state of the art, comparison of algorithms, interpretability, and future directions.

Chapter 3 outlines the research methodology, including research design, data collection and preprocessing, feature selection and engineering, model development, evaluation, performance metrics, cross-validation, hyperparameter tuning, ethical considerations, statistical analysis, and software tools. Chapter 4 discusses the findings of the study, including model performance, factors influencing performance, clinical relevance of features, comparisons with existing models, limitations, implications for practice, and recommendations for future research.

Finally, Chapter 5 presents the conclusion and summary of the thesis, summarizing the findings, contributions to the field, practical implications, limitations, future research directions, and concluding remarks. By exploring the use of machine learning in predicting patient mortality, this thesis contributes to the growing body of literature on predictive modeling in healthcare and highlights the potential of machine learning in improving patient outcomes.

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