Pharmacological strategies for neuroprotection in epilepsy – Complete Phd and Masters Thesis

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Introduction

Epilepsy is a neurological disorder characterized by recurrent seizures, affecting approximately 50 million people worldwide. Despite the availability of antiepileptic drugs, many patients with epilepsy continue to experience seizures and suffer from cognitive impairments and neuronal damage. Therefore, there is a growing interest in developing pharmacological strategies for neuroprotection in epilepsy to prevent or minimize the neuronal damage associated with seizures.

Chapter 1: Introduction
1.1 Introduction
1.2 Background of study
1.3 Problem Statement
1.4 Objective of study
1.5 Limitation of study
1.6 Scope of study
1.7 Significance of study
1.8 Structure of the Thesis
1.9 Definition of terms

Chapter 2: Literature Review
2.1 Overview of epilepsy
2.2 Neuroprotective mechanisms in epilepsy
2.3 Current pharmacological strategies for neuroprotection in epilepsy
2.4 Neurotrophic factors in epilepsy
2.5 Antioxidants in epilepsy
2.6 Anti-inflammatory agents in epilepsy
2.7 Calcium channel blockers in epilepsy
2.8 Glutamate receptor antagonists in epilepsy
2.9 GABA receptor modulators in epilepsy
2.10 Summary of literature review

Chapter 3: Research Methodology
3.1 Research design
3.2 Study population
3.3 Data collection methods
3.4 Data analysis
3.5 Ethical considerations
3.6 Statistical analysis
3.7 Research limitations
3.8 Research implications

Chapter 4: Discussion of Findings
4.1 Overview of study findings
4.2 Neuroprotective effects of pharmacological agents in epilepsy
4.3 Mechanisms of action of neuroprotective agents in epilepsy
4.4 Comparison of different pharmacological strategies for neuroprotection in epilepsy
4.5 Future directions for research in pharmacological neuroprotection in epilepsy

Chapter 5: Conclusion and Summary
5.1 Summary of findings
5.2 Implications for clinical practice
5.3 Limitations of the study
5.4 Recommendations for future research
5.5 Conclusion

Thesis Overview:

Epilepsy is a neurological disorder affecting millions of people worldwide, characterized by recurrent seizures and associated neuronal damage. Despite the availability of antiepileptic drugs, many patients continue to suffer from seizures and cognitive impairments. This thesis focuses on pharmacological strategies for neuroprotection in epilepsy, aiming to prevent or minimize neuronal damage associated with seizures.

The literature review will highlight current neuroprotective mechanisms in epilepsy and discuss various pharmacological strategies, including neurotrophic factors, antioxidants, anti-inflammatory agents, calcium channel blockers, and glutamate receptor antagonists. The research methodology will outline the study design, population, data collection methods, and ethical considerations.

The discussion of findings will analyze the neuroprotective effects of pharmacological agents in epilepsy, their mechanisms of action, and compare different strategies for neuroprotection. The conclusion will summarize the findings, implications for clinical practice, limitations of the study, and provide recommendations for future research.

Overall, this thesis aims to contribute to the growing body of knowledge on pharmacological strategies for neuroprotection in epilepsy, ultimately improving the quality of life for patients with epilepsy.

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