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Introduction

Lichen planus is a chronic inflammatory skin condition that affects the skin, mucous membranes, hair, and nails. It is characterized by itchy, flat-topped, polygonal papules that can coalesce to form plaques. The exact cause of lichen planus is unknown, but it is believed to be an autoimmune disorder where the immune system mistakenly attacks the skin and mucous membranes. There are various treatment options available for lichen planus, including topical and systemic medications. This thesis aims to explore pharmacological interventions in lichen planus, specifically focusing on the effectiveness and safety of these treatments.

Chapter 1: Introduction
1.1 Introduction
1.2 Background of study
1.3 Problem Statement
1.4 Objective of study
1.5 Limitation of study
1.6 Scope of study
1.7 Significance of study
1.8 Structure of the Thesis
1.9 Definition of terms

Chapter 2: Literature Review
2.1 Overview of lichen planus
2.2 Pathophysiology of lichen planus
2.3 Current treatment options for lichen planus
2.4 Topical corticosteroids
2.5 Systemic corticosteroids
2.6 Retinoids
2.7 Calcineurin inhibitors
2.8 Antihistamines
2.9 Immunosuppressants
2.10 Novel pharmacological interventions in lichen planus

Chapter 3: Research Methodology
3.1 Research design
3.2 Study population
3.3 Data collection methods
3.4 Data analysis
3.5 Ethical considerations
3.6 Sampling techniques
3.7 Study variables
3.8 Statistical analysis

Chapter 4: Discussion of Findings
4.1 Efficacy of topical corticosteroids in lichen planus
4.2 Safety profile of systemic corticosteroids in lichen planus
4.3 Role of retinoids in the treatment of lichen planus
4.4 Efficacy of calcineurin inhibitors in lichen planus
4.5 Antihistamines in lichen planus management
4.6 Immunosuppressants for severe lichen planus
4.7 Comparison of different pharmacological interventions
4.8 Adverse effects of pharmacological treatments
4.9 Patient compliance and satisfaction
4.10 Future research directions

Chapter 5: Conclusion and Summary
In conclusion, pharmacological interventions play a crucial role in the management of lichen planus. This thesis has discussed the various treatment options available, their efficacy, safety profile, and patient satisfaction. It is essential for healthcare providers to be aware of these pharmacological interventions to provide optimal care for patients with lichen planus. Further research is needed to explore new treatment modalities and improve patient outcomes in lichen planus management.

Thesis Overview:
Pharmacological interventions in lichen planus have evolved over the years, with a wide range of treatment options available for patients. This thesis aims to provide a comprehensive overview of the pharmacological interventions in lichen planus, focusing on their efficacy, safety profile, and patient satisfaction. The literature review will explore the current treatment options, including topical corticosteroids, systemic corticosteroids, retinoids, calcineurin inhibitors, antihistamines, and immunosuppressants. The research methodology will outline the study design, data collection methods, and statistical analysis. The discussion of findings will evaluate the efficacy and safety of different pharmacological interventions, while the conclusion and summary will summarize the key findings and suggest future research directions. Overall, this thesis will contribute to the existing knowledge on pharmacological interventions in lichen planus and provide valuable insights for healthcare providers and researchers in the field.

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