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Introduction

Hidradenitis suppurativa (HS) is a chronic inflammatory skin disease characterized by recurrent painful nodules, abscesses, and sinus tracts in the apocrine gland-bearing areas of the body. It is a debilitating condition that significantly impacts the quality of life of affected individuals. While the exact etiology of HS remains unclear, it is believed to involve a complex interplay of genetic, immunologic, and environmental factors. Currently, there is no cure for HS, and treatment options are limited. Pharmacological interventions, including antibiotics, immunomodulators, and biologics, are commonly used to manage the symptoms of HS and improve patient outcomes.

This thesis aims to provide a comprehensive overview of pharmacological interventions in the management of HS. The following chapters will explore the background of the study, the problem statement, the objectives of the study, the limitations and scope of the study, the significance of the study, the structure of the thesis, and the definition of terms related to pharmacological interventions in HS. Additionally, a literature review will be conducted to summarize the current evidence on pharmacological interventions for HS, followed by a discussion of the research methodology, findings, and conclusions.

Table of Contents

Chapter 1: Introduction
1.1 Introduction
1.2 Background of Study
1.3 Problem Statement
1.4 Objective of Study
1.5 Limitation of Study
1.6 Scope of Study
1.7 Significance of Study
1.8 Structure of the Thesis
1.9 Definition of Terms

Chapter 2: Literature Review
2.1 Overview of Hidradenitis Suppurativa
2.2 Antibiotics in the Management of HS
2.3 Immunomodulators in the Management of HS
2.4 Biologics in the Management of HS
2.5 Other Pharmacological Interventions in HS
2.6 Efficacy and Safety of Pharmacological Interventions in HS
2.7 Adherence to Pharmacological Interventions in HS
2.8 Patient Satisfaction with Pharmacological Interventions in HS
2.9 Gaps in the Literature
2.10 Summary of Literature Review

Chapter 3: Research Methodology
3.1 Research Design
3.2 Population and Sample Selection
3.3 Data Collection Methods
3.4 Data Analysis
3.5 Ethical Considerations
3.6 Validity and Reliability
3.7 Research Limitations
3.8 Future Directions

Chapter 4: Discussion of Findings
4.1 Overview of Study Results
4.2 Comparison with Existing Literature
4.3 Implications for Clinical Practice
4.4 Limitations of the Study
4.5 Recommendations for Future Research

Chapter 5: Conclusion and Summary
5.1 Summary of Key Findings
5.2 Implications for Pharmacological Interventions in HS
5.3 Future Directions for Research
5.4 Conclusion

In conclusion, this thesis will provide valuable insights into the current landscape of pharmacological interventions in the management of HS. By synthesizing the existing literature and presenting new research findings, this study aims to contribute to the growing body of knowledge on this challenging skin condition.

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