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Introduction

Olfactory Reference Syndrome (ORS) is a psychiatric disorder characterized by a persistent belief that one emits a foul or offensive body odor, despite evidence to the contrary. This syndrome often leads to significant distress and impairment in social and occupational functioning. Despite its debilitating effects, ORS remains poorly understood, with limited effective treatment options available.

In recent years, there has been increasing interest in identifying novel targets for the treatment of ORS. These targets may include specific neurotransmitter systems, neural circuits, or genetic factors that play a role in the development and maintenance of ORS symptoms. Understanding these novel targets may lead to the development of more effective treatments for this challenging disorder.

This thesis aims to explore novel targets in ORS in order to advance our understanding of the underlying mechanisms of the disorder and to identify potential new avenues for treatment. The following chapters will provide a comprehensive overview of the background literature on ORS, present the research methodology used in this study, discuss the findings, and offer conclusions and implications for future research and clinical practice.

Table of Contents
Chapter 1: Introduction
1.1 Introduction
1.2 Background of Study
1.3 Problem Statement
1.4 Objective of Study
1.5 Limitation of Study
1.6 Scope of Study
1.7 Significance of Study
1.8 Structure of the Thesis
1.9 Definition of Terms

Chapter 2: Literature Review
2.1 Overview of Olfactory Reference Syndrome
2.2 Etiology and Risk Factors
2.3 Current Treatment Approaches
2.4 Neurobiological Basis of ORS
2.5 Genetic Factors
2.6 Cognitive and Behavioral Factors
2.7 Comorbidities
2.8 Diagnostic Challenges
2.9 Prognosis and Long-Term Outcomes
2.10 Gaps in the Literature

Chapter 3: Research Methodology
3.1 Research Design
3.2 Participants
3.3 Measures
3.4 Data Collection Procedures
3.5 Data Analysis
3.6 Ethical Considerations
3.7 Study Limitations
3.8 Future Directions

Chapter 4: Discussion of Findings
4.1 Summary of Results
4.2 Comparison with Previous Research
4.3 Implications for Theory and Practice
4.4 Limitations of the Study
4.5 Recommendations for Future Research

Chapter 5: Conclusion and Summary
5.1 Summary of Key Findings
5.2 Clinical and Research Implications
5.3 Concluding Remarks
5.4 Recommendations for Practitioners and Policy Makers
5.5 Limitations of the Study
5.6 Directions for Future Research

Thesis Overview: Novel Targets in Olfactory Reference Syndrome

Olfactory Reference Syndrome (ORS) is a psychiatric disorder characterized by the mistaken belief that one emits a foul body odor. This syndrome can have profound effects on individuals’ mental health and quality of life. Despite increased recognition of ORS in recent years, there remains a lack of effective treatment options available. The aim of this thesis is to explore novel targets in ORS that may offer new insights into the underlying mechanisms of the disorder and pave the way for the development of more effective interventions.

The thesis begins with a comprehensive introduction that outlines the background of the study, the problem statement, objectives, limitations, scope, significance, and structure of the thesis. Chapter two presents a detailed literature review of ORS, covering aspects such as etiology, current treatment approaches, neurobiological and genetic factors, comorbidities, diagnostic challenges, and prognosis. Chapter three describes the research methodology employed in this study, including research design, participant selection, measures, data collection procedures, analysis, ethical considerations, limitations, and future directions.

Chapter four presents a discussion of the findings, including a summary of results, comparison with previous research, implications for theory and practice, limitations of the study, and recommendations for future research. Finally, chapter five offers a conclusion and summary of key findings, along with clinical and research implications, concluding remarks, recommendations for practitioners and policymakers, limitations, and directions for future research.

Overall, this thesis aims to contribute to the growing body of literature on ORS by identifying novel targets for intervention. By advancing our understanding of the underlying mechanisms of ORS and exploring new avenues for treatment, this research has the potential to make a meaningful impact on the lives of individuals struggling with this challenging disorder.

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