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Introduction

Drug resistance remains a major challenge in cancer treatment, leading to treatment failures and disease progression. Traditional cancer therapies, such as chemotherapy and targeted therapy, often become ineffective as cancer cells develop resistance mechanisms. In recent years, novel approaches have emerged to overcome drug resistance and improve the outcomes of cancer treatment. This thesis aims to explore and evaluate these novel approaches in the context of overcoming drug resistance in cancer.

Chapter 1: Introduction
1.1 Introduction
1.2 Background of study
1.3 Problem Statement
1.4 Objective of study
1.5 Limitation of study
1.6 Scope of study
1.7 Significance of study
1.8 Structure of the Thesis
1.9 Definition of terms

Chapter 2: Literature Review
2.1 Overview of drug resistance in cancer
2.2 Mechanisms of drug resistance in cancer
2.3 Traditional approaches to overcoming drug resistance
2.4 Novel targeted therapies in drug-resistant cancers
2.5 Immunotherapy in drug-resistant cancers
2.6 Nanotechnology in overcoming drug resistance
2.7 Epigenetic modifications in drug resistance
2.8 Tumor microenvironment and drug resistance
2.9 Clinical trials on novel approaches to drug-resistant cancers
2.10 Future directions in overcoming drug resistance

Chapter 3: Research Methodology
3.1 Research design
3.2 Data collection methods
3.3 Study population
3.4 Data analysis
3.5 Ethical considerations
3.6 Pilot study
3.7 Validity and reliability
3.8 Limitations of the study

Chapter 4: Discussion of Findings
4.1 Analysis of research results
4.2 Comparison with existing literature
4.3 Implications for clinical practice
4.4 Recommendations for future research
4.5 Strengths and limitations of the study

Chapter 5: Conclusion and Summary
5.1 Summary of key findings
5.2 Contributions to the field
5.3 Implications for clinical practice
5.4 Recommendations for future research
5.5 Conclusion

Thesis Overview: Novel approaches to overcome drug resistance in cancer

Drug resistance is a major obstacle in the effective treatment of cancer. As cancer cells evolve and adapt to treatment, they can become resistant to traditional therapies, leading to treatment failures and disease progression. In recent years, novel approaches have emerged to overcome drug resistance and improve outcomes for cancer patients. This thesis aims to explore and evaluate these novel approaches in the context of overcoming drug resistance in cancer.

Chapter 1 provides an introduction to the topic, including the background of the study, problem statement, objectives, limitations, scope, significance, and structure of the thesis. Chapter 2 presents a comprehensive literature review on drug resistance in cancer, including mechanisms, traditional approaches, and novel targeted therapies.

Chapter 3 outlines the research methodology, including design, data collection, analysis, study population, ethical considerations, and validity. Chapter 4 discusses the findings of the study, including analysis, comparison with existing literature, implications for practice, recommendations, and limitations.

Finally, Chapter 5 offers a conclusion and summary of the key findings, contributions to the field, implications for practice, recommendations for future research, and a conclusive statement. This thesis aims to contribute to the growing body of knowledge on novel approaches to overcome drug resistance in cancer, with the ultimate goal of improving outcomes for cancer patients.

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