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Introduction

Neurovascular dysfunction is a key component of vascular dementia, a common form of cognitive impairment resulting from decreased blood flow to the brain. This dysfunction can lead to a cascade of events including oxidative stress, inflammation, and neuronal damage, ultimately contributing to cognitive decline. Understanding the underlying mechanisms of neurovascular dysfunction in vascular dementia is crucial for developing effective treatment strategies and improving patient outcomes.

Chapter 1: Introduction

1.1 Introduction
1.2 Background of Study
1.3 Problem Statement
1.4 Objective of Study
1.5 Limitation of Study
1.6 Scope of Study
1.7 Significance of Study
1.8 Structure of the Thesis
1.9 Definition of Terms

Chapter 2: Literature Review

2.1 Overview of Vascular Dementia
2.2 Neurovascular Dysfunction in Vascular Dementia
2.3 Mechanisms of Neurovascular Dysfunction
2.4 Risk Factors for Neurovascular Dysfunction
2.5 Current Treatment Strategies for Vascular Dementia
2.6 Neuroimaging Biomarkers of Neurovascular Dysfunction
2.7 Animal Models of Neurovascular Dysfunction
2.8 Clinical Studies on Neurovascular Dysfunction
2.9 Future Directions in Research
2.10 Gaps in the Literature

Chapter 3: Research Methodology

3.1 Research Design
3.2 Participants
3.3 Data Collection Methods
3.4 Data Analysis
3.5 Ethical Considerations
3.6 Validity and Reliability
3.7 Pilot Testing
3.8 Limitations of the Research

Chapter 4: Discussion of Findings

4.1 Overview of Study Findings
4.2 Comparison with Existing Literature
4.3 Implications for Clinical Practice
4.4 Implications for Future Research
4.5 Strengths and Limitations of the Study
4.6 Recommendations for Healthcare Providers
4.7 Recommendations for Policy Makers
4.8 Conclusion

Chapter 5: Conclusion and Summary

In conclusion, neurovascular dysfunction plays a critical role in the pathogenesis of vascular dementia. By elucidating the underlying mechanisms and risk factors associated with this dysfunction, we can develop targeted interventions to improve patient outcomes and quality of life. This thesis aims to contribute to the growing body of knowledge on neurovascular dysfunction in vascular dementia and provide insights for future research and clinical practice.

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