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Introduction:
Excoriation disorder, also known as skin-picking disorder, is a psychological condition characterized by recurrent picking at one’s skin, resulting in skin lesions and significant distress or impairment in daily functioning. Despite being classified as a distinct disorder in the DSM-5, the underlying mechanisms and neurobiological factors contributing to excoriation disorder remain poorly understood. One potential avenue of investigation is the role of neurotransmitter dynamics in the development and maintenance of this disorder.
This thesis aims to explore the neurobiological underpinnings of excoriation disorder, focusing specifically on the role of neurotransmitters in the pathophysiology of the condition. By examining the intricate interplay between neurotransmitter systems and skin-picking behaviors, this study seeks to shed light on the underlying mechanisms driving this maladaptive behavior and to inform the development of more effective treatment strategies for individuals suffering from excoriation disorder.
Chapter 1: Introduction
1.1 Introduction
1.2 Background of study
1.3 Problem Statement
1.4 Objective of study
1.5 Limitation of study
1.6 Scope of study
1.7 Significance of study
1.8 Structure of the Thesis
1.9 Definition of terms
Chapter 2: Literature Review
2.1 Overview of excoriation disorder
2.2 Neurotransmitter systems implicated in excoriation disorder
2.3 Serotonin and excoriation disorder
2.4 Dopamine and excoriation disorder
2.5 Glutamate and excoriation disorder
2.6 GABA and excoriation disorder
2.7 Neurotransmitter dysregulation in other compulsive disorders
2.8 Neurobiological models of excoriation disorder
2.9 Pharmacological interventions targeting neurotransmitter systems
2.10 Gaps in the current literature
Chapter 3: Research Methodology
3.1 Research design
3.2 Participants
3.3 Measures
3.4 Data collection procedures
3.5 Data analysis
3.6 Ethical considerations
3.7 Pilot study
3.8 Validity and reliability of measures
Chapter 4: Discussion of Findings
4.1 Overview of findings
4.2 Implications for understanding excoriation disorder
4.3 Clinical implications
4.4 Future directions for research
4.5 Limitations of the study
4.6 Strengths of the study
4.7 Comparison with existing literature
4.8 Recommendations for clinical practice
Chapter 5: Conclusion and Summary
5.1 Summary of key findings
5.2 Contribution to the field
5.3 Clinical implications
5.4 Limitations and future directions
5.5 Conclusion
Thesis Overview on Neurotransmitter dynamics in excoriation disorder:
Excoriation disorder, also known as skin-picking disorder, is a psychiatric condition that is characterized by repetitive picking at one’s skin, leading to skin lesions and significant impairment in daily functioning. Although excoriation disorder is a relatively common psychiatric condition, the underlying neurobiological mechanisms driving this maladaptive behavior remain poorly understood. This thesis aims to investigate the role of neurotransmitter dynamics in the pathophysiology of excoriation disorder, with a specific focus on the involvement of serotonin, dopamine, glutamate, and GABA systems in the development and maintenance of this disorder.
Chapter 1 provides an Introduction to the study, presenting the background, problem statement, objectives, limitations, scope, significance, and structure of the thesis. Chapter 2 conducts a comprehensive Literature Review on excoriation disorder, neurotransmitter systems implicated in the disorder, neurobiological models, and pharmacological interventions targeting neurotransmitter systems. Chapter 3 outlines the Research Methodology, detailing the research design, participants, measures, data collection procedures, data analysis, ethical considerations, pilot study, and validity and reliability of measures. Chapter 4 presents a detailed Discussion of Findings, including an overview of results, implications, clinical implications, future directions for research, limitations, strengths, and recommendations for clinical practice. Finally, Chapter 5 offers a Conclusion and Summary, summarizing key findings, contributions to the field, clinical implications, limitations and future directions, and concluding remarks. This thesis aims to enhance our understanding of the neurobiological underpinnings of excoriation disorder and to guide the development of more effective treatment approaches for individuals suffering from this debilitating condition.
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