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Introduction

Neuropathic pain is a complex and debilitating condition that affects millions of individuals worldwide. It is characterized by persistent pain that arises from damage or dysfunction of the nervous system. Despite advances in pharmacological and non-pharmacological treatments, a significant number of patients with neuropathic pain continue to experience inadequate pain relief and adverse side effects. Neuromodulation has emerged as a promising treatment modality for chronic neuropathic pain, offering a novel approach to pain management by targeting specific neural pathways involved in the pain process.

Chapter 1: Introduction
1.1 Introduction
1.2 Background of study
1.3 Problem Statement
1.4 Objective of study
1.5 Limitation of study
1.6 Scope of study
1.7 Significance of study
1.8 Structure of the Thesis
1.9 Definition of Terms

Chapter 2: Literature Review
2.1 Overview of Neuropathic Pain
2.2 Current Treatments for Neuropathic Pain
2.3 Mechanisms of Neuromodulation
2.4 Types of Neuromodulation Techniques
2.5 Efficacy of Neuromodulation in Chronic Neuropathic Pain
2.6 Safety and Side Effects of Neuromodulation
2.7 Cost-effectiveness of Neuromodulation
2.8 Patient Selection for Neuromodulation
2.9 Future Directions in Neuromodulation Research
2.10 Gaps in the Literature

Chapter 3: Research Methodology
3.1 Research Design
3.2 Participants
3.3 Interventions
3.4 Outcome Measures
3.5 Data Collection Procedures
3.6 Data Analysis
3.7 Ethical Considerations
3.8 Limitations of the Study

Chapter 4: Discussion of Findings
4.1 Overview of Study Results
4.2 Comparison with Existing Literature
4.3 Implications for Clinical Practice
4.4 Strengths and Limitations of the Study
4.5 Recommendations for Future Research

Chapter 5: Conclusion and Summary
5.1 Summary of Key Findings
5.2 Implications for Practice
5.3 Limitations of the Study
5.4 Conclusion

Thesis Overview

Neuromodulation for chronic neuropathic pain has gained increasing attention as a potential treatment option for patients with refractory pain conditions. This thesis aims to provide a comprehensive overview of the current state of knowledge on the use of neuromodulation in the management of chronic neuropathic pain. The introduction will highlight the background, problem statement, objectives, significance, and structure of the thesis. The literature review will explore the mechanisms, types, efficacy, safety, and future directions of neuromodulation in chronic neuropathic pain. The research methodology section will outline the design, participants, interventions, outcome measures, data analysis, and ethical considerations of the study. The discussion of findings will present an in-depth analysis of the study results, their implications for clinical practice, and recommendations for future research. The conclusion will summarize the key findings, discuss their implications, and highlight the limitations of the study. Overall, this thesis will contribute to the growing body of evidence supporting the use of neuromodulation in the management of chronic neuropathic pain.

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