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Introduction:

Neuroimaging has revolutionized our understanding of brain function and dysfunction in various neurological disorders. One such disorder is neglect syndrome, a condition characterized by the inability to attend to stimuli on one side of space, typically following a stroke or brain injury. Neglect syndrome poses a significant challenge to patients’ daily functioning and rehabilitation efforts due to its complex and variable nature.

This thesis aims to explore the neural mechanisms underlying spatial attention in neglect syndrome using neuroimaging techniques. By examining the brain regions and networks involved in spatial attention and their alterations in neglect patients, this study seeks to provide insights into the pathophysiology of neglect syndrome and potential targets for therapeutic interventions.

Chapter 1: Introduction
1.1 Introduction
1.2 Background of the study
1.3 Problem Statement
1.4 Objective of the study
1.5 Limitation of the study
1.6 Scope of the study
1.7 Significance of the study
1.8 Structure of the Thesis
1.9 Definition of terms

Chapter 2: Literature Review
2.1 Overview of neglect syndrome
2.2 Theories of spatial attention
2.3 Neuroimaging techniques in neglect research
2.4 Neural correlates of spatial attention
2.5 Functional and structural brain alterations in neglect syndrome
2.6 Cognitive rehabilitation approaches for neglect syndrome
2.7 Neuroplasticity mechanisms in neglect recovery
2.8 Behavioral and neuroimaging predictors of neglect prognosis
2.9 Challenges and controversies in neglect research
2.10 Gaps in the literature and research directions

Chapter 3: Research Methodology
3.1 Research design
3.2 Participants
3.3 Neuroimaging methods
3.4 Task paradigm
3.5 Data analysis
3.6 Statistical analysis
3.7 Ethical considerations
3.8 Validity and reliability
3.9 Potential biases
3.10 Timeline and budget

Chapter 4: Discussion of Findings
4.1 Neural correlates of spatial attention in neglect syndrome
4.2 Brain regions and networks involved in neglect recovery
4.3 Neuroplasticity mechanisms underlying neglect rehabilitation
4.4 Implications for clinical practice
4.5 Comparative analysis with existing literature
4.6 Study limitations and future directions

Chapter 5: Conclusion and Summary
5.1 Summary of key findings
5.2 Contributions to the field
5.3 Practical implications
5.4 Recommendations for future research
5.5 Conclusion

Thesis Overview:

Neuroimaging of spatial attention in neglect syndrome is a complex and multifaceted research area that requires a comprehensive understanding of neuroanatomy, cognitive neuroscience, and clinical neurology. This thesis aims to bridge the gap between basic research and clinical application by investigating the neural mechanisms underlying spatial attention deficits in neglect syndrome using advanced neuroimaging techniques.

The literature review will provide a comprehensive overview of neglect syndrome, theories of spatial attention, neuroimaging methods, neural correlates of spatial attention, brain alterations in neglect patients, rehabilitation approaches, neuroplasticity mechanisms, predictors of neglect recovery, challenges in neglect research, and gaps in the literature.

The research methodology will outline the study design, participant selection criteria, neuroimaging methods, task paradigm, data analysis procedures, statistical analysis, ethical considerations, validity and reliability checks, potential biases, and project timeline and budget.

The discussion of findings will present the results of the neuroimaging study, including neural correlates of spatial attention in neglect syndrome, brain regions and networks involved in neglect recovery, neuroplasticity mechanisms, implications for clinical practice, comparative analysis with existing literature, study limitations, and future research directions.

In conclusion, this thesis will highlight the importance of neuroimaging in understanding spatial attention deficits in neglect syndrome and suggest potential avenues for improving patient outcomes through targeted rehabilitation interventions and neuroplasticity-based therapies.

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