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Introduction

Traumatic brain injury (TBI) is a significant public health concern, with an estimated 69 million incidents occurring worldwide each year. TBI is known to have a detrimental impact on various cognitive functions, including memory. Among the different types of memory, prospective memory (PM) is of particular interest due to its relevance to everyday functioning and quality of life. PM refers to the ability to remember to carry out intentions or plans in the future, and impairments in PM have been reported in individuals with TBI.

Neuroimaging techniques, such as functional magnetic resonance imaging (fMRI) and positron emission tomography (PET), have provided valuable insights into the neural mechanisms underlying PM in healthy individuals. However, there is a paucity of research on the neuroimaging correlates of PM in individuals with TBI. Understanding the neural basis of PM impairments in TBI can guide the development of targeted interventions to improve cognitive outcomes in this population.

This thesis aims to investigate the neuroimaging correlates of PM in individuals with TBI. Specifically, this study will utilize fMRI to examine the neural networks involved in PM tasks in TBI patients. The findings from this research have the potential to advance our understanding of cognitive deficits in TBI and inform the development of evidence-based interventions for this population.

1.2 Background of Study
1.3 Problem Statement
1.4 Objective of Study
1.5 Limitation of Study
1.6 Scope of Study
1.7 Significance of Study
1.8 Structure of the Thesis
1.9 Definition of Terms

Chapter Two: Literature Review
2.1 Introduction to Traumatic Brain Injury
2.2 Prospective Memory and its Neural Correlates
2.3 Neuroimaging Techniques in Traumatic Brain Injury
2.4 Previous Studies on Prospective Memory in Traumatic Brain Injury
2.5 Cognitive Rehabilitation in Traumatic Brain Injury
2.6 Theoretical Framework
2.7 Gaps in the Literature
2.8 Summary of Literature Review
2.9 Hypotheses Development

Chapter Three: Research Methodology
3.1 Research Design
3.2 Participants
3.3 Measures
3.4 Procedure
3.5 Data Analysis
3.6 Ethics Considerations
3.7 Data Collection
3.8 Power Analysis

Chapter Four: Discussion of Findings
4.1 Descriptive Statistics
4.2 Behavioral Results
4.3 Neuroimaging Results
4.4 Comparison with Previous Studies
4.5 Implications for Cognitive Rehabilitation
4.6 Limitations of the Study
4.7 Future Directions
4.8 Conclusions

Chapter Five: Conclusion and Summary
5.1 Summary of Findings
5.2 Contributions to the Field
5.3 Practical Implications
5.4 Recommendations for Future Research
5.5 Conclusion

Thesis Overview on Neuroimaging of Prospective Memory in Traumatic Brain Injury

Traumatic brain injury (TBI) is a significant public health issue that can result in various cognitive deficits, including impairments in prospective memory (PM). PM refers to the ability to remember to perform intended actions in the future, and deficits in PM can have a significant impact on daily functioning and quality of life in individuals with TBI. Neuroimaging techniques, such as functional magnetic resonance imaging (fMRI), provide a unique opportunity to examine the neural mechanisms underlying PM in TBI patients.

This thesis aims to investigate the neuroimaging correlates of PM in individuals with TBI, using fMRI to examine the neural networks involved in PM tasks. By elucidating the neural basis of PM impairments in TBI, this research has the potential to inform the development of targeted cognitive rehabilitation interventions for this population. The study design includes a comprehensive literature review, an exploration of the theoretical framework, a detailed methodology section, a discussion of findings, and a conclusion summarizing the key findings and their implications.

Overall, this thesis contributes to the growing body of literature on cognitive deficits in TBI and provides valuable insights into the neural mechanisms underlying PM impairments in this population. By advancing our understanding of the cognitive sequelae of TBI, this research has the potential to improve the quality of life and functional outcomes for individuals living with TBI.

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