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Introduction

Neuroimaging techniques have revolutionized our understanding of brain structure and function, providing crucial insights into the neurobiological basis of cognitive processes. Prospective memory, the ability to remember to perform intended actions in the future, is a complex cognitive function that is essential for maintaining independence in daily life. Mild cognitive impairment (MCI) represents a transitional state between normal aging and dementia, and individuals with MCI often experience deficits in prospective memory.

This thesis aims to investigate the neural correlates of prospective memory in individuals with MCI using neuroimaging techniques. By examining the structural and functional brain changes associated with prospective memory impairment in MCI, this study seeks to enhance our understanding of the underlying pathology and contribute to the development of targeted interventions for this population.

Chapter 1: Introduction
1.1 Introduction
1.2 Background of study
1.3 Problem Statement
1.4 Objective of study
1.5 Limitation of study
1.6 Scope of study
1.7 Significance of study
1.8 Structure of the Thesis
1.9 Definition of terms

Chapter 2: Literature Review
2.1 Overview of Prospective Memory
2.2 Mild Cognitive Impairment
2.3 Neuroimaging Techniques
2.4 Prospective Memory in MCI
2.5 Structural Brain Changes in MCI
2.6 Functional Brain Changes in MCI
2.7 Neuroimaging Studies of Prospective Memory in MCI
2.8 Cognitive Reserve and Prospective Memory
2.9 Interventions for Prospective Memory Impairment in MCI
2.10 Theoretical Framework

Chapter 3: Research Methodology
3.1 Research Design
3.2 Participants
3.3 Neuroimaging Modalities
3.4 Prospective Memory Assessment
3.5 Data Analysis
3.6 Ethical Considerations
3.7 Study Procedures
3.8 Data Collection

Chapter 4: Discussion of Findings
4.1 Structural Brain Changes in Prospective Memory
4.2 Functional Brain Changes in Prospective Memory
4.3 Neural Correlates of Prospective Memory Impairment in MCI
4.4 Relationship between Cognitive Reserve and Prospective Memory
4.5 Implications for Interventions
4.6 Theoretical Implications
4.7 Methodological Considerations
4.8 Future Directions

Chapter 5: Conclusion and Summary
5.1 Summary of Findings
5.2 Implications for Clinical Practice
5.3 Recommendations for Future Research
5.4 Conclusion

Thesis Overview

Neuroimaging of prospective memory in mild cognitive impairment is a critical area of research that aims to uncover the neural mechanisms underlying prospective memory impairment in individuals with MCI. This thesis will provide a comprehensive review of the existing literature on prospective memory, MCI, and neuroimaging techniques, as well as present the methodology and findings of an original study on this topic.

The introduction will set the stage by outlining the background, problem statement, objectives, limitations, scope, significance, and structure of the thesis. Furthermore, key terms will be defined to ensure clarity and understanding of the subsequent chapters.

The literature review will delve into various aspects of prospective memory, MCI, neuroimaging, and related topics to provide a solid theoretical foundation for the study. This section will synthesize existing research findings and highlight gaps in the literature that the current study aims to address.

The research methodology chapter will detail the study design, participant selection, neuroimaging modalities, prospective memory assessment, data analysis, ethical considerations, and study procedures. It will provide a roadmap for how the study was conducted and ensure transparency and reproducibility.

The discussion of findings chapter will present the results of the neuroimaging study, analyzing structural and functional brain changes associated with prospective memory impairment in MCI. The implications of these findings for interventions, theoretical frameworks, and future research directions will be discussed in detail.

In the conclusion and summary chapter, the main findings of the study will be summarized, and their implications for clinical practice and future research will be highlighted. Recommendations for further study in this area will be provided, and the overall significance of the research will be underscored.

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