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Introduction

Major Depressive Disorder (MDD) is a common mental health condition that affects millions of people worldwide. One of the hallmark symptoms of MDD is deficits in prospective memory, which is the ability to remember and perform intended actions at a future point in time. Neuroimaging techniques, such as functional magnetic resonance imaging (fMRI) and positron emission tomography (PET), have been instrumental in studying the neural mechanisms underlying prospective memory in MDD. Understanding the neural underpinnings of prospective memory in MDD can help in developing more effective treatments and interventions for individuals suffering from this debilitating condition.

Chapter 1: Introduction
1.1 Introduction
1.2 Background of study
1.3 Problem Statement
1.4 Objective of study
1.5 Limitation of study
1.6 Scope of study
1.7 Significance of study
1.8 Structure of the Thesis
1.9 Definition of terms

Chapter 2: Literature Review
2.1 Overview of Major Depressive Disorder
2.2 Prospective Memory Deficits in Major Depressive Disorder
2.3 Neuroimaging Techniques in Major Depressive Disorder
2.4 Neural Correlates of Prospective Memory in Major Depressive Disorder
2.5 Cognitive and Neural Mechanisms of Prospective Memory
2.6 Functional Neuroanatomy of Prospective Memory
2.7 Neuroimaging Studies on Prospective Memory in Major Depressive Disorder
2.8 Neurobiological Basis of Major Depressive Disorder
2.9 Prospective Memory and Treatment Outcomes in Major Depressive Disorder
2.10 Theoretical Frameworks in Understanding Prospective Memory in Major Depressive Disorder

Chapter 3: Research Methodology
3.1 Research Design
3.2 Participants
3.3 Measures
3.4 Procedure
3.5 Neuroimaging Data Acquisition
3.6 Data Analysis
3.7 Statistical Analysis
3.8 Ethical Considerations

Chapter 4: Discussion of Findings
4.1 Prospective Memory Performance in Major Depressive Disorder
4.2 Neural Correlates of Prospective Memory in Major Depressive Disorder
4.3 Implications for Treatment and Interventions
4.4 Future Directions
4.5 Strengths and Limitations of the Study

Chapter 5: Conclusion and Summary
5.1 Summary of Findings
5.2 Implications for Clinical Practice
5.3 Recommendations for Future Research
5.4 Conclusion

Thesis Overview:

Neuroimaging of prospective memory in major depressive disorder is a comprehensive examination of the neural mechanisms underlying prospective memory deficits in individuals with MDD. This thesis explores the cognitive and neural basis of prospective memory in MDD, utilizing neuroimaging techniques to investigate the brain regions involved in prospective memory tasks. By integrating findings from previous studies and conducting novel analyses, this thesis aims to contribute to our understanding of the neural underpinnings of prospective memory deficits in MDD.

Chapter 1 provides the introduction to the study, outlining the background, problem statement, objectives, limitations, scope, significance, structure, and definition of terms. Chapter 2 presents a thorough review of the existing literature on MDD, prospective memory deficits, neuroimaging techniques, neural correlates of prospective memory in MDD, and theoretical frameworks. Chapter 3 details the research methodology, including research design, participants, measures, procedure, neuroimaging data acquisition, data analysis, statistical analysis, and ethical considerations.

Chapter 4 discusses the findings of the study, focusing on prospective memory performance in MDD, neural correlates of prospective memory, implications for treatment and interventions, and future directions. Finally, Chapter 5 offers a conclusion and summary of the study, highlighting the key findings, implications for clinical practice, recommendations for future research, and concluding remarks. This thesis aims to provide valuable insights into the neurobiological basis of prospective memory deficits in MDD and suggests potential avenues for improving treatment outcomes for individuals with this condition.

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