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Introduction

Pathological skin picking, also known as excoriation disorder or dermatillomania, is a psychiatric condition characterized by the repeated urge to pick at one’s own skin, resulting in skin lesions and tissue damage. This behavior can be detrimental to one’s physical and mental well-being, often leading to embarrassment, shame, and social isolation. Despite the prevalence of this disorder, the neurobiological mechanisms underlying pathological skin picking remain poorly understood.

This thesis aims to explore the neurobiology of pathological skin picking, with a focus on the underlying brain circuits and neurotransmitter systems involved in this compulsive behavior. By investigating the neural basis of skin picking, we hope to gain insights into potential therapeutic targets and interventions for individuals suffering from this debilitating disorder.

Chapter 1: Introduction
1.1 Introduction
1.2 Background of Study
1.3 Problem Statement
1.4 Objective of Study
1.5 Limitation of Study
1.6 Scope of Study
1.7 Significance of Study
1.8 Structure of the Thesis
1.9 Definition of Terms

Chapter 2: Literature Review
2.1 Overview of Pathological Skin Picking
2.2 Prevalence and Clinical Features
2.3 Etiology and Risk Factors
2.4 Neurobiological Basis of Compulsive Behaviors
2.5 Neurotransmitter Systems Implicated in Skin Picking
2.6 Brain Imaging Studies in Pathological Skin Picking
2.7 Animal Models of Compulsive Skin Picking
2.8 Current Treatment Approaches
2.9 Gaps in the Literature
2.10 Future Directions

Chapter 3: Research Methodology
3.1 Research Design
3.2 Participant Recruitment
3.3 Data Collection Procedures
3.4 Neuroimaging Protocols
3.5 Data Analysis
3.6 Ethical Considerations
3.7 Validity and Reliability
3.8 Limitations of the Study

Chapter 4: Discussion of Findings
4.1 Neurobiological Correlates of Pathological Skin Picking
4.2 Implications for Treatment and Intervention
4.3 Comparative Analysis with Other Compulsive Behaviors
4.4 Future Research Directions
4.5 Clinical Relevance and Practical Applications

Chapter 5: Conclusion and Summary
5.1 Summary of Findings
5.2 Contributions to the Field
5.3 Limitations and Implications for Future Research
5.4 Recommendations for Clinical Practice

Thesis Overview

Pathological skin picking, or excoriation disorder, is a complex psychiatric condition characterized by recurrent and compulsive picking at one’s own skin, leading to tissue damage and psychological distress. Despite the growing recognition of this disorder, there is a lack of understanding of the underlying neurobiological mechanisms driving this behavior.

This thesis aims to address this gap by investigating the neurobiology of pathological skin picking, with a focus on the brain circuits and neurotransmitter systems involved in this compulsive behavior. By synthesizing existing literature and conducting original research, we seek to uncover the neural basis of skin picking and explore potential therapeutic interventions for individuals affected by this disorder.

Through a comprehensive review of the current literature, an examination of neuroimaging studies, and an analysis of animal models of compulsive behaviors, this thesis will provide a deeper understanding of the neurobiological correlates of pathological skin picking. The research methodology section will outline the design and procedures of our study, including participant recruitment, data collection, and analysis protocols.

The discussion of findings section will present the results of our research, highlighting the neurobiological underpinnings of skin picking and their implications for treatment and intervention. By elucidating the neural mechanisms driving this compulsive behavior, we hope to inform clinical practice and contribute to the development of targeted therapeutic approaches for individuals with pathological skin picking.

In conclusion, this thesis will offer a comprehensive overview of the neurobiology of pathological skin picking, shedding light on the underlying mechanisms of this disorder and paving the way for future research in this field. By bridging the gap between neuroscience and clinical psychology, we aim to provide valuable insights into the treatment and management of pathological skin picking, ultimately improving the quality of life for individuals affected by this debilitating condition.

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