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Introduction

Neuropsychiatric lupus and autoimmune encephalopathies are conditions that involve the immune system attacking the central nervous system, leading to a range of neurological and psychiatric symptoms. These conditions can have a significant impact on the quality of life of affected individuals, and there is still much to be understood about the underlying neurobiology of these disorders.

This thesis aims to explore the neurobiology of neuropsychiatric lupus and autoimmune encephalopathies in order to gain a better understanding of the mechanisms that underlie these conditions. By doing so, we hope to contribute to the development of more effective treatments and interventions for individuals suffering from these disorders.

Chapter 1: Introduction
1.1 Introduction
1.2 Background of study
1.3 Problem Statement
1.4 Objective of study
1.5 Limitation of study
1.6 Scope of study
1.7 Significance of study
1.8 Structure of the Thesis
1.9 Definition of terms

Chapter 2: Literature Review
2.1 Overview of neuropsychiatric lupus and autoimmune encephalopathies
2.2 Neurobiological mechanisms of autoimmune encephalopathies
2.3 Relationship between lupus and neuropsychiatric symptoms
2.4 Current treatment approaches for neuropsychiatric lupus
2.5 The role of inflammation in neuropsychiatric lupus
2.6 Autoimmune encephalopathies and cognitive dysfunction
2.7 Neuroimaging findings in autoimmune encephalopathies
2.8 Genetic and environmental factors in the development of autoimmune encephalopathies
2.9 Neuropsychiatric manifestations of systemic lupus erythematosus
2.10 Neuropsychiatric systemic lupus erythematosus and risk factors for cognitive impairment

Chapter 3: Research Methodology
3.1 Research design
3.2 Participants
3.3 Data collection methods
3.4 Data analysis procedures
3.5 Ethical considerations
3.6 Sampling techniques
3.7 Instrumentation
3.8 Data validity and reliability

Chapter 4: Discussion of Findings
4.1 Neurobiological mechanisms underlying neuropsychiatric lupus
4.2 Common neuroimaging findings in autoimmune encephalopathies
4.3 Implications for treatment and intervention
4.4 Future research directions
4.5 Limitations of the study

Chapter 5: Conclusion and Summary
5.1 Summary of key findings
5.2 Implications for clinical practice
5.3 Recommendations for future research
5.4 Conclusion

Thesis Overview

The neurobiology of neuropsychiatric lupus and autoimmune encephalopathies is a complex and evolving field of study. This thesis aims to bring together current knowledge on the neurobiological mechanisms that underlie these conditions, as well as to identify gaps in our understanding that warrant further research.

By conducting a comprehensive literature review, examining the latest research findings, and proposing a research methodology to investigate these conditions further, this thesis seeks to contribute to the growing body of knowledge on neuropsychiatric lupus and autoimmune encephalopathies. Ultimately, our goal is to improve our understanding of these disorders and to develop more effective treatments for individuals affected by them.

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