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**Introduction**

The neurobiology of aging and dementia is a complex field of study that seeks to understand the biological processes that underlie the aging brain and the development of cognitive decline and dementia in older adults. As the global population continues to age, the prevalence of age-related cognitive disorders such as Alzheimer’s disease is on the rise, making this a critical area of research. This thesis aims to provide a comprehensive overview of the current understanding of the neurobiology of aging and dementia, with a focus on potential mechanisms, risk factors, and potential interventions to delay or prevent cognitive decline.

**Table of Content**

1.1 Introduction

1.2 Background of Study

1.3 Problem Statement

1.4 Objective of Study

1.5 Limitation of Study

1.6 Scope of Study

1.7 Significance of Study

1.8 Structure of the Thesis

1.9 Definition of Terms

**Chapter Two: Literature Review**

2.1 The Aging Brain: Normal vs. Pathological Changes

2.2 Risk Factors for Cognitive Decline and Dementia

2.3 Neurobiological Mechanisms of Aging and Dementia

2.4 Genetic Factors in Cognitive Aging

2.5 Neuroinflammation and Oxidative Stress in Aging and Dementia

2.6 Diagnostic Biomarkers for Dementia

2.7 Current Treatment Strategies for Dementia

2.8 Lifestyle Interventions for Cognitive Health

2.9 Emerging Therapeutic Approaches for Alzheimer’s Disease

2.10 Future Directions in Research on Aging and Dementia

**Chapter Three: Research Methodology**

3.1 Research Design

3.2 Study Population

3.3 Data Collection Methods

3.4 Data Analysis Techniques

3.5 Ethical Considerations

3.6 Limitations of the Study

3.7 Validity and Reliability of Findings

3.8 Research Timeline

**Chapter Four: Discussion of Findings**

4.1 Summary of Results

4.2 Comparison with Existing Literature

4.3 Implications for Practice

4.4 Recommendations for Future Research

**Chapter Five: Conclusion and Summary**

5.1 Summary of Key Findings

5.2 Conclusions

5.3 Implications for Clinical Practice

5.4 Limitations of the Study

5.5 Recommendations for Future Research

**Thesis Overview: Neurobiology of Aging and Dementia**

The neurobiology of aging and dementia is a complex and rapidly growing field of study that is of critical importance in our aging society. This thesis provides a comprehensive review of the current understanding of the neurobiological mechanisms underlying aging and dementia, including genetic, environmental, and lifestyle factors that contribute to cognitive decline. The literature review synthesizes current research on risk factors, diagnostic biomarkers, and treatment strategies for dementia, while the research methodology outlines the design, methods, and ethical considerations of the study. The discussion of findings highlights key results and their implications for practice, as well as recommendations for future research. Overall, this thesis aims to contribute to our understanding of aging and dementia and inform future research and clinical practice in this important area.

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