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Introduction

Schizophrenia is a chronic and severe mental disorder that affects how a person thinks, feels, and behaves. One of the core symptoms of schizophrenia is cognitive deficits, including impairments in attention, working memory, and executive function. These cognitive deficits have a significant impact on the daily functioning and quality of life of individuals with schizophrenia.

Cognitive training has emerged as a promising treatment approach for alleviating cognitive deficits in individuals with schizophrenia. Cognitive training programs aim to improve cognitive function through targeted exercises and practice. While the effectiveness of cognitive training in schizophrenia has been well-documented, the underlying neurobiological mechanisms that drive the cognitive improvements observed with training remain unclear.

This thesis aims to explore the neurobiological mechanisms of cognitive training for schizophrenia. By investigating the neural changes associated with cognitive training, this research seeks to deepen our understanding of how cognitive deficits in schizophrenia can be effectively targeted and improved through training interventions.

Table of Contents

Chapter 1: Introduction
1.1 Introduction
1.2 Background of study
1.3 Problem Statement
1.4 Objective of study
1.5 Limitation of study
1.6 Scope of study
1.7 Significance of study
1.8 Structure of the Thesis
1.9 Definition of Terms

Chapter 2: Literature Review
2.1 Cognitive deficits in schizophrenia
2.2 Cognitive training interventions
2.3 Neurobiological basis of cognitive deficits in schizophrenia
2.4 Neuroplasticity and cognitive training
2.5 Neural correlates of cognitive training in schizophrenia
2.6 Neuroimaging techniques in cognitive training research
2.7 Pharmacological interventions and cognitive training
2.8 Individual differences in response to cognitive training
2.9 Future directions in cognitive training research for schizophrenia
2.10 Summary of literature review

Chapter 3: Research Methodology
3.1 Research design
3.2 Participant recruitment
3.3 Cognitive training intervention
3.4 Neuroimaging assessments
3.5 Data analysis
3.6 Ethical considerations
3.7 Measures of cognitive function
3.8 Timeline for data collection and analysis

Chapter 4: Discussion of Findings
4.1 Neural changes associated with cognitive training
4.2 Relationship between cognitive improvements and neural changes
4.3 Implications for cognitive training interventions
4.4 Limitations of the study
4.5 Future directions for research
4.6 Comparison with existing literature on neurobiological mechanisms of cognitive training in schizophrenia

Chapter 5: Conclusion
5.1 Summary of key findings
5.2 Implications for clinical practice
5.3 Recommendations for future research
5.4 Conclusion and final thoughts

This thesis will provide a comprehensive overview of the neurobiological mechanisms underlying cognitive training for schizophrenia, with the aim of enhancing our understanding of how cognitive deficits can be effectively addressed in individuals with this mental disorder. By synthesizing existing literature and presenting original research findings, this thesis will contribute to the growing body of knowledge in the field of cognitive training interventions for schizophrenia.

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