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Introduction

Autism spectrum disorder (ASD) is a complex developmental disorder characterized by deficits in social communication and interaction, as well as restricted, repetitive patterns of behavior, interests, or activities. The prevalence of ASD has been increasing, with current estimates suggesting that 1 in 54 children in the United States are diagnosed with ASD. Despite the growing awareness and interest in ASD, the precise neurobiological mechanisms underlying this disorder remain unclear.

This thesis aims to explore the neurobiological basis of ASD, focusing on the underlying neural circuits, genetic factors, and environmental influences that contribute to the development of this disorder. By gaining a better understanding of the neurobiological basis of ASD, we hope to provide insights into potential therapeutic interventions and improve outcomes for individuals with ASD.

Chapter 1: Introduction
1.1 Introduction
1.2 Background of study
1.3 Problem Statement
1.4 Objective of study
1.5 Limitation of study
1.6 Scope of study
1.7 Significance of study
1.8 Structure of the Thesis
1.9 Definition of terms

Chapter 2: Literature Review
2.1 Overview of Autism Spectrum Disorder
2.2 Neurobiological Theories of ASD
2.3 Genetic Factors in ASD
2.4 Environmental Influences on ASD
2.5 Neuroimaging Studies in ASD
2.6 Neurotransmitter Systems in ASD
2.7 Immune System Dysregulation in ASD
2.8 Epigenetic Mechanisms in ASD
2.9 Animal Models of ASD
2.10 Current Treatment Approaches for ASD

Chapter 3: Research Methodology
3.1 Research Design
3.2 Participants
3.3 Data Collection Methods
3.4 Data Analysis Procedures
3.5 Ethical Considerations
3.6 Validity and Reliability
3.7 Pilot Study
3.8 Research Limitations

Chapter 4: Discussion of Findings
4.1 Overview of Findings
4.2 Neurobiological Mechanisms of ASD
4.3 Implications for Future Research
4.4 Clinical Applications
4.5 Challenges and Limitations
4.6 Conclusions

Chapter 5: Conclusion and Summary
5.1 Summary of Findings
5.2 Implications for Practice
5.3 Recommendations for Future Research
5.4 Conclusion

Thesis Overview

Autism spectrum disorder (ASD) is a complex neurodevelopmental disorder with a strong genetic component. Research on the neurobiological basis of ASD has identified several key factors that contribute to the development of this disorder, including alterations in neural circuits, genetic mutations, and environmental influences. This thesis aims to provide a comprehensive overview of the current understanding of the neurobiological basis of ASD, with a focus on potential therapeutic interventions and future research directions.

Chapter 1 introduces the topic of ASD and provides an overview of the research aims and objectives. The literature review in Chapter 2 synthesizes current knowledge on the neurobiological mechanisms of ASD, including genetic factors, neuroimaging studies, and animal models. Chapter 3 outlines the research methodology, including data collection methods and ethical considerations. In Chapter 4, the findings of the study are discussed in relation to existing literature, highlighting the implications for clinical practice and future research. Finally, Chapter 5 presents a summary of the key findings and conclusions of the thesis. Together, these chapters provide a comprehensive analysis of the neurobiological basis of ASD and offer insights into potential interventions and treatment approaches for individuals with this disorder.

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