Neural correlates of anosognosia in Alzheimerʼs disease – Complete Phd and Masters Thesis

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Introduction

Anosognosia, the lack of awareness of one’s own illness or deficits, is a common symptom in patients with Alzheimerʼs disease. Despite the high prevalence and negative impact of anosognosia on the quality of life of Alzheimerʼs disease patients, the neural correlates underlying this symptom remain largely unknown. Understanding the neural mechanisms of anosognosia in Alzheimerʼs disease is crucial for developing effective interventions and improving patient care.

Chapter 1: Introduction
1.1 Introduction
1.2 Background of study
1.3 Problem Statement
1.4 Objective of study
1.5 Limitation of study
1.6 Scope of study
1.7 Significance of study
1.8 Structure of the Thesis
1.9 Definition of terms

Chapter 2: Literature Review
2.1 Introduction to Alzheimerʼs disease
2.2 Anosognosia in Alzheimerʼs disease
2.3 Neural correlates of anosognosia
2.4 Cognitive dysfunction in Alzheimerʼs disease
2.5 Structural and functional brain changes in Alzheimerʼs disease
2.6 Neuroimaging studies of anosognosia in Alzheimerʼs disease
2.7 Behavioral manifestations of anosognosia
2.8 Factors influencing anosognosia in Alzheimerʼs disease
2.9 Anosognosia and caregiver burden
2.10 Current treatment approaches for anosognosia in Alzheimerʼs disease

Chapter 3: Research Methodology
3.1 Research design
3.2 Participants
3.3 Measures
3.4 Procedure
3.5 Data analysis
3.6 Ethical considerations
3.7 Validity and reliability
3.8 Statistical analysis

Chapter 4: Discussion of Findings
4.1 Overview of findings
4.2 Neural correlates of anosognosia
4.3 Cognitive deficits and anosognosia
4.4 Brain structural and functional changes
4.5 Neuroimaging evidence
4.6 Behavioral manifestations
4.7 Factors influencing anosognosia
4.8 Implications for treatment and care

Chapter 5: Conclusion and Summary
5.1 Summary of findings
5.2 Contributions to the field
5.3 Recommendations for future research
5.4 Conclusion

Thesis Overview on Neural Correlates of Anosognosia in Alzheimerʼs Disease

Anosognosia, the lack of awareness of one’s own illness or deficits, is a common and challenging symptom in patients with Alzheimerʼs disease. Despite its high prevalence and negative impact on patient care, the neural correlates underlying anosognosia in Alzheimerʼs disease remain poorly understood. This thesis aims to address this gap in the literature by investigating the neural mechanisms of anosognosia in Alzheimerʼs disease.

The introduction provides background information on Alzheimerʼs disease, anosognosia, and the need for further research in this area. The literature review explores current knowledge on cognitive dysfunction, structural and functional brain changes, neuroimaging studies, behavioral manifestations, and treatment approaches related to anosognosia in Alzheimerʼs disease.

The research methodology outlines the study design, participant selection, measures, procedure, data analysis, ethical considerations, and validity and reliability of the study. The discussion of findings highlights the neural correlates of anosognosia, cognitive deficits, brain structural and functional changes, neuroimaging evidence, behavioral manifestations, and factors influencing anosognosia in Alzheimerʼs disease.

The conclusion summarizes key findings, discusses their implications, and provides recommendations for future research in this area. Overall, this thesis aims to enhance our understanding of anosognosia in Alzheimerʼs disease and contribute to the development of more effective interventions and improved patient care.

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