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Introduction

Frontotemporal dementia (FTD) is a neurodegenerative disorder characterized by progressive decline in behavior, language, and executive function. One of the key cognitive deficits observed in individuals with FTD is impairment in theory of mind (ToM), the ability to infer mental states of others. This impairment in ToM has significant impact on social interactions and relationships, leading to increased caregiver burden and decreased quality of life for both patients and their families.

Understanding the neural basis of ToM impairment in FTD is critical for developing effective interventions to support individuals with FTD in maintaining their social functioning and improving their quality of life. This thesis aims to explore the neural mechanisms underlying ToM impairment in FTD, with a focus on the frontotemporal regions of the brain that are known to be affected in this disorder.

Chapter 1: Introduction

1.1 Introduction
1.2 Background of study
1.3 Problem Statement
1.4 Objective of study
1.5 Limitation of study
1.6 Scope of study
1.7 Significance of study
1.8 Structure of the Thesis
1.9 Definition of Terms

Chapter 2: Literature Review

2.1 Overview of Frontotemporal Dementia
2.2 Theory of Mind in Neurotypical Individuals
2.3 Theory of Mind Impairment in Frontotemporal Dementia
2.4 Neural Basis of Theory of Mind
2.5 Neuroimaging Studies on Theory of Mind in Frontotemporal Dementia
2.6 Behavioral Studies on Theory of Mind in Frontotemporal Dementia
2.7 Treatment Approaches for Theory of Mind Impairment in Frontotemporal Dementia
2.8 Challenges in Assessing Theory of Mind in Frontotemporal Dementia
2.9 Theoretical Frameworks for Understanding Theory of Mind in Frontotemporal Dementia

Chapter 3: Research Methodology

3.1 Research Design
3.2 Participants
3.3 Measures
3.4 Procedure
3.5 Data Analysis
3.6 Ethical Considerations
3.7 Validity and Reliability
3.8 Limitations of the Study

Chapter 4: Discussion of Findings

4.1 Overview of Study Findings
4.2 Neural Correlates of Theory of Mind Impairment in Frontotemporal Dementia
4.3 Implications for Clinical Practice and Interventions
4.4 Future Directions for Research
4.5 Comparison with Previous Studies
4.6 Strengths and Limitations of the Study

Chapter 5: Conclusion and Summary

5.1 Summary of Findings
5.2 Implications of the Study
5.3 Recommendations for Practice
5.4 Contributions to the Field
5.5 Future Research Directions

Thesis Overview:

Frontotemporal dementia (FTD) is a debilitating neurodegenerative disorder that affects the frontotemporal regions of the brain, leading to progressive decline in behavior, language, and executive function. One of the key cognitive deficits observed in individuals with FTD is impairment in theory of mind (ToM), the ability to infer mental states of others. This impairment in ToM has significant impact on social interactions and relationships, leading to increased caregiver burden and decreased quality of life for both patients and their families.

This thesis aims to explore the neural basis of ToM impairment in FTD, with a focus on the frontotemporal regions of the brain that are known to be affected in this disorder. The literature review will provide an overview of FTD, ToM in neurotypical individuals, ToM impairment in FTD, and the neural basis of ToM. The research methodology will outline the design, participants, measures, procedure, and data analysis for the study. The discussion of findings will present the results of the study, implications for clinical practice, future research directions, and limitations of the study. The conclusion and summary will summarize the findings, discuss the implications of the study, make recommendations for practice, and suggest future research directions. By elucidating the neural mechanisms underlying ToM impairment in FTD, this thesis aims to contribute to the understanding of FTD and improve the care and support for individuals with this devastating illness.

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