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Introduction

Vascular dementia is the second most common form of dementia after Alzheimer’s disease, characterized by cognitive impairment due to impaired blood flow to the brain. Neurovascular dysfunction, which refers to impairment in the regulation of blood flow in the brain, has been implicated in the pathogenesis of vascular dementia. Understanding the mechanisms underlying neurovascular dysfunction in vascular dementia is crucial for the development of novel therapeutic strategies for this debilitating condition.

Chapter 1: Introduction
1.1 Introduction
1.2 Background of study
1.3 Problem Statement
1.4 Objective of study
1.5 Limitation of study
1.6 Scope of study
1.7 Significance of study
1.8 Structure of the Thesis
1.9 Definition of terms

Chapter 2: Literature Review
2.1 Introduction to vascular dementia
2.2 Pathophysiology of vascular dementia
2.3 Neurovascular coupling in vascular dementia
2.4 Blood-brain barrier dysfunction in vascular dementia
2.5 Neuroinflammation in vascular dementia
2.6 Imaging techniques in the study of neurovascular dysfunction
2.7 Therapeutic targets for neurovascular dysfunction in vascular dementia
2.8 Current research gaps in the field
2.9 Summary

Chapter 3: Research Methodology
3.1 Research design
3.2 Participants
3.3 Data collection methods
3.4 Data analysis techniques
3.5 Ethical considerations
3.6 Statistical analysis
3.7 Research limitations
3.8 Research implications
3.9 Summary

Chapter 4: Discussion of Findings
4.1 Overview of study findings
4.2 Neurovascular dysfunction in vascular dementia
4.3 Implications for diagnosis and treatment
4.4 Comparison with existing literature
4.5 Future research directions
4.6 Strengths and limitations of the study
4.7 Conclusion

Chapter 5: Conclusion and Summary
5.1 Summary of findings
5.2 Implications for clinical practice
5.3 Contributions to the field
5.4 Recommendations for future research
5.5 Conclusion

Thesis Overview on Investigation of Neurovascular Dysfunction in Vascular Dementia

Vascular dementia is a progressive cognitive disorder caused by impaired blood flow to the brain, leading to neurovascular dysfunction. This thesis aims to investigate the mechanisms underlying neurovascular dysfunction in vascular dementia and its implications for diagnosis and treatment.

Chapter 1 provides an introduction to the topic, including background information, problem statement, objectives, limitations, scope, significance, structure of the thesis, and definition of terms.

Chapter 2 presents a comprehensive review of the literature on vascular dementia, neurovascular coupling, blood-brain barrier dysfunction, neuroinflammation, imaging techniques, therapeutic targets, and current research gaps in the field.

Chapter 3 outlines the research methodology, including research design, participants, data collection methods, data analysis techniques, ethical considerations, statistical analysis, limitations, and implications of the study.

Chapter 4 discusses the findings of the study, including an overview of neurovascular dysfunction in vascular dementia, implications for diagnosis and treatment, comparison with existing literature, future research directions, and strengths and limitations of the study.

Chapter 5 concludes the thesis by summarizing the findings, discussing implications for clinical practice, highlighting contributions to the field, making recommendations for future research, and providing a conclusion.

Overall, this thesis aims to advance our understanding of neurovascular dysfunction in vascular dementia and contribute to the development of novel therapeutic strategies for this debilitating condition.

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