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Introduction:

Biologics, also known as biological products, are a class of medications that are derived from living organisms or their products. These complex molecules have revolutionized the treatment of various diseases, including cancer, autoimmune disorders, and chronic inflammatory conditions. However, the pharmacokinetics of biologics can be quite different from traditional small molecule drugs, presenting unique challenges in terms of dosing, administration, and monitoring.

The aim of this thesis is to investigate the pharmacokinetics of biologics, with a focus on understanding their absorption, distribution, metabolism, and excretion in the body. By gaining a better understanding of how these molecules behave in the body, we hope to optimize their therapeutic effects and minimize the risk of adverse reactions.

Chapter 1: Introduction
1.1 Introduction
1.2 Background of study
1.3 Problem Statement
1.4 Objective of study
1.5 Limitation of study
1.6 Scope of study
1.7 Significance of study
1.8 Structure of the Thesis
1.9 Definition of terms

Chapter 2: Literature Review
2.1 Overview of biologics
2.2 Pharmacokinetics of biologics
2.3 Factors influencing pharmacokinetics
2.4 Clinical applications of biologics
2.5 Challenges in biologics pharmacokinetics
2.6 Current trends in biologics research
2.7 Regulatory considerations
2.8 Pharmacokinetic modeling
2.9 Bioanalytical methods
2.10 Future directions

Chapter 3: Research Methodology
3.1 Study design
3.2 Data collection
3.3 Data analysis
3.4 In vitro studies
3.5 In vivo studies
3.6 Sample preparation
3.7 Analytical techniques
3.8 Statistical analysis

Chapter 4: Discussion of Findings
4.1 Pharmacokinetic profiles of biologics
4.2 Impact of dosing regimen
4.3 Drug-drug interactions
4.4 Immunogenicity
4.5 Patient variability
4.6 Therapeutic drug monitoring
4.7 Clinical implications
4.8 Comparison with small molecule drugs

Chapter 5: Conclusion and Summary
5.1 Key findings
5.2 Implications for clinical practice
5.3 Future research directions
Overall, this thesis aims to contribute to the growing body of knowledge on the pharmacokinetics of biologics, with the ultimate goal of improving patient outcomes and advancing the field of precision medicine. By investigating the intricate workings of these complex molecules, we hope to unlock new possibilities for personalized and effective therapies.

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