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Introduction

The field of biomedical engineering has made significant advancements in the development of artificial hearts as a means of providing life-saving support for patients with end-stage heart failure. However, the design and optimization of artificial hearts present unique challenges, particularly in understanding the complex fluid dynamics of blood flow within the device. Fluid dynamics simulation has emerged as a powerful tool for studying the behavior of blood flow in artificial hearts, offering insights into the performance and design considerations of these critical life-saving devices.

Chapter 1: Introduction
1.1 Introduction
1.2 Background of study
1.3 Problem Statement
1.4 Objective of study
1.5 Limitation of study
1.6 Scope of study
1.7 Significance of study
1.8 Structure of the Thesis
1.9 Definition of terms

Chapter 2: Literature Review
2.1 Overview of artificial hearts
2.2 Fluid dynamics in cardiovascular systems
2.3 Computational fluid dynamics in biomedical engineering
2.4 Previous studies on blood flow in artificial hearts
2.5 Design considerations in artificial heart development
2.6 Fluid-structure interaction in artificial hearts
2.7 Hemocompatibility of artificial heart materials
2.8 Clinical outcomes of artificial heart implantation
2.9 Challenges in artificial heart design
2.10 Future directions in artificial heart research

Chapter 3: System Design and Methodology
3.1 Selection of simulation software
3.2 Model development of artificial heart geometry
3.3 Boundary conditions and material properties
3.4 Mesh generation and refinement
3.5 Fluid dynamics simulation setup
3.6 Post-processing and data analysis
3.7 Validation of simulation results
3.8 Sensitivity analysis of key parameters

Chapter 4: System Implementation
4.1 Integration of simulation results with experimental data
4.2 Optimization of artificial heart design based on simulation findings
4.3 Comparison of different artificial heart configurations
4.4 Assessment of fluid dynamics performance metrics
4.5 Evaluation of hemodynamic parameters
4.6 Validation of simulation results with in vitro studies
4.7 Visualization of blood flow patterns in artificial hearts
4.8 Computational efficiency and scalability of simulation model

Chapter 5: Conclusion and Summary
In this chapter, we will summarize the key findings of the study, discuss the implications of our results for the field of artificial heart research, and provide recommendations for future research directions. We will also highlight the contributions of this thesis to the field of fluid dynamics simulation in biomedical engineering and its potential impact on the development of next-generation artificial hearts.

Thesis Overview

The aim of this thesis is to investigate the fluid dynamics of blood flow in artificial hearts using computational fluid dynamics simulation. The study will focus on understanding the complex interactions between fluid flow and the structural components of artificial hearts, with the goal of optimizing the design and performance of these life-saving devices. The thesis will begin with an introduction to the topic, followed by a comprehensive review of relevant literature in the field of artificial hearts, fluid dynamics, and computational modeling. The system design and methodology chapter will detail the simulation setup, model development, and validation procedures. The system implementation chapter will present the results of the simulation study, including the evaluation of fluid dynamics performance metrics and visualization of blood flow patterns in artificial hearts. The conclusion and summary chapter will provide a concise overview of the key findings and potential implications of the study, as well as recommendations for future research in the field. Overall, this thesis aims to contribute to the advancement of artificial heart technology through the application of computational fluid dynamics simulation to study blood flow dynamics in these critical medical devices.

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