Exploring the use of transcranial direct current stimulation for the treatment of obsessive-compulsive disorder (OCD) – Complete Phd and Masters Thesis

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Introduction

Obsessive-compulsive disorder (OCD) is a debilitating mental health disorder characterized by intrusive thoughts (obsessions) and repetitive behaviors (compulsions) that significantly impair daily functioning. Traditional treatment approaches for OCD, such as cognitive-behavioral therapy and pharmacological interventions, have been effective for many individuals. However, a significant portion of patients do not respond adequately to these treatments, highlighting the need for alternative and innovative interventions.

Transcranial Direct Current Stimulation (tDCS) is a non-invasive brain stimulation technique that has shown promise in the treatment of various psychiatric disorders, including depression, schizophrenia, and addiction. tDCS involves the application of low-intensity electrical currents to specific regions of the brain through electrodes placed on the scalp. By modulating neural activity, tDCS has the potential to target the underlying neurobiological mechanisms of OCD and offer a novel therapeutic approach for individuals who do not respond to traditional treatments.

This thesis aims to explore the use of tDCS for the treatment of OCD, with a specific focus on its efficacy, safety, and mechanisms of action. By conducting a comprehensive literature review, implementing a rigorous research methodology, and analyzing the findings, this study seeks to advance our understanding of the potential benefits of tDCS in the management of OCD symptoms.

Chapter 1: Introduction
1.1 Introduction
1.2 Background of study
1.3 Problem Statement
1.4 Objective of study
1.5 Limitation of study
1.6 Scope of study
1.7 Significance of study
1.8 Structure of the Thesis
1.9 Definition of terms

Chapter 2: Literature Review
2.1 Overview of OCD
2.2 Current Treatment Approaches for OCD
2.3 Neurobiological Underpinnings of OCD
2.4 Transcranial Direct Current Stimulation (tDCS)
2.5 Previous Studies on tDCS for OCD
2.6 Safety and Tolerability of tDCS
2.7 Potential Mechanisms of Action of tDCS in OCD
2.8 Theoretical Framework for the Use of tDCS in OCD
2.9 Gaps in the Literature
2.10 Conclusion

Chapter 3: Research Methodology
3.1 Research Design
3.2 Participant Recruitment
3.3 Intervention Protocol
3.4 Outcome Measures
3.5 Data Collection Procedures
3.6 Data Analysis Plan
3.7 Ethical Considerations
3.8 Study Limitations

Chapter 4: Discussion of Findings
4.1 Participant Characteristics
4.2 Efficacy of tDCS in Reducing OCD Symptoms
4.3 Safety and Tolerability of tDCS
4.4 Mechanisms of Action of tDCS in OCD
4.5 Comparison with Previous Studies
4.6 Implications for Clinical Practice
4.7 Future Directions
4.8 Study Limitations
4.9 Conclusion

Chapter 5: Conclusion and Summary
5.1 Summary of Findings
5.2 Implications for Research and Practice
5.3 Limitations of the Study
5.4 Recommendations for Future Research
5.5 Conclusion

Thesis Overview

Obsessive-compulsive disorder (OCD) is a challenging mental health condition that affects millions of people worldwide. Although cognitive-behavioral therapy and medication are commonly used treatments, a significant portion of individuals with OCD do not experience symptom relief. In recent years, transcranial direct current stimulation (tDCS) has emerged as a potential alternative therapy for OCD, offering a novel approach to modulating brain activity and reducing symptoms.

This thesis explores the use of tDCS for the treatment of OCD, with a focus on its efficacy, safety, and underlying mechanisms of action. By conducting a thorough literature review, implementing a rigorous research methodology, and analyzing the findings, this study aims to contribute to the growing body of knowledge on the potential benefits of tDCS in managing OCD symptoms. Through a structured exploration of the literature, research methodology, discussion of findings, and conclusion, this thesis seeks to provide insight into the effectiveness of tDCS as a treatment option for individuals with OCD.

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