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Introduction

Long non-coding RNAs (lncRNAs) have emerged as important regulators of gene expression and have been implicated in various biological processes, including immune responses. In infectious diseases, the host immune system plays a critical role in recognizing and eliminating pathogens. However, the regulation of immune responses in the context of infectious diseases is complex and not fully understood. Recent studies have highlighted the potential role of lncRNAs in modulating immune responses during infectious diseases. Therefore, this thesis aims to explore the role of lncRNAs in the regulation of immune responses in infectious diseases.

1.1 Introduction
1.2 Background of study
1.3 Problem Statement
1.4 Objective of study
1.5 Limitation of study
1.6 Scope of study
1.7 Significance of study
1.8 Structure of the Thesis
1.9 Definition of terms

Chapter Two: Literature Review
2.1 Overview of lncRNAs
2.2 lncRNAs in immune responses
2.3 lncRNAs in infectious diseases
2.4 The role of lncRNAs in regulating immune responses in infectious diseases
2.5 Methods for studying lncRNAs
2.6 Current research gaps
2.7 Summary of key findings in the literature
2.8 The potential of lncRNAs as therapeutic targets
2.9 Challenges in studying lncRNAs
2.10 Future directions in lncRNA research

Chapter Three: Research Methodology
3.1 Research design
3.2 Sample collection
3.3 RNA isolation and quantification
3.4 Analysis of lncRNA expression levels
3.5 In vitro and in vivo experiments
3.6 Statistical analysis
3.7 Bioinformatics analysis
3.8 Ethical considerations

Chapter Four: Discussion of Findings
4.1 Analysis of lncRNA expression profiles in infectious diseases
4.2 Functional roles of lncRNAs in regulating immune responses
4.3 Crosstalk between lncRNAs and immune signaling pathways
4.4 Implications of lncRNA dysregulation in infectious diseases
4.5 Comparison with existing literature
4.6 Future research directions
4.7 Limitations of the study
4.8 The potential clinical relevance of lncRNAs as biomarkers or therapeutic targets

Chapter Five: Conclusion and Summary
5.1 Summary of key findings
5.2 Implications of the study
5.3 Contributions to the field
5.4 Recommendations for future research
5.5 Conclusion

Thesis Overview:

The intricate interplay between non-coding RNAs and immune responses in infectious diseases has garnered increasing interest in recent years. Long non-coding RNAs (lncRNAs), in particular, have emerged as crucial regulators of gene expression and immune signaling pathways. This thesis aims to explore the role of lncRNAs in the regulation of immune responses in infectious diseases.

Chapter one provides an introduction to the research topic, including the background, problem statement, objectives, limitations, scope, significance, and structure of the thesis. Chapter two conducts a comprehensive literature review on lncRNAs, immune responses, infectious diseases, and the potential role of lncRNAs in modulating immune responses during infectious diseases.

Chapter three details the research methodology, including study design, sample collection, RNA isolation, experimental techniques, analysis methods, and ethical considerations. Chapter four presents a detailed discussion of the findings, including the analysis of lncRNA expression profiles, functional roles of lncRNAs in immune regulation, crosstalk with immune signaling pathways, and implications of lncRNA dysregulation in infectious diseases.

Chapter five summarizes the key findings, discusses the implications of the study, highlights contributions to the field, suggests future research directions, and concludes the thesis. This project aims to advance our understanding of how lncRNAs regulate immune responses in infectious diseases, with potential implications for the development of novel therapeutic strategies.

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