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Introduction

Central line-associated bloodstream infections (CLABSIs) are a significant problem in healthcare settings, leading to increased morbidity, mortality, and healthcare costs. Nurse-led interventions have been shown to be effective in reducing CLABSIs, but there is a need for further evaluation of these interventions to determine their effectiveness and impact on patient outcomes. This thesis aims to evaluate nurse-led interventions to reduce CLABSIs and contribute to the body of knowledge on infection prevention in healthcare settings.

Chapter 1: Introduction
1.1 Introduction
1.2 Background of study
1.3 Problem Statement
1.4 Objective of study
1.5 Limitation of study
1.6 Scope of study
1.7 Significance of study
1.8 Structure of the Thesis
1.9 Definition of terms

Chapter 2: Literature Review
2.1 Overview of CLABSIs
2.2 Risk factors for CLABSIs
2.3 Nurse-led interventions to reduce CLABSIs
2.4 Effectiveness of nurse-led interventions
2.5 Implementation strategies for nurse-led interventions
2.6 Barriers to implementing nurse-led interventions
2.7 Patient outcomes related to nurse-led interventions
2.8 Cost-effectiveness of nurse-led interventions
2.9 Gaps in the literature
2.10 Theoretical framework

Chapter 3: Research Methodology
3.1 Research design
3.2 Population and sample
3.3 Data collection methods
3.4 Data analysis
3.5 Ethical considerations
3.6 Validity and reliability
3.7 Pilot study
3.8 Data management
3.9 Research limitations

Chapter 4: Discussion of Findings
4.1 Overview of study findings
4.2 Comparison of nurse-led interventions
4.3 Factors influencing the effectiveness of interventions
4.4 Implications for practice
4.5 Recommendations for future research
4.6 Strengths and limitations of the study

Chapter 5: Conclusion and Summary
5.1 Summary of key findings
5.2 Implications for nursing practice
5.3 Contribution to the field
5.4 Limitations of the study
5.5 Recommendations for future research
5.6 Conclusion

Thesis Overview:

Central line-associated bloodstream infections (CLABSIs) are a significant problem in healthcare settings, leading to increased morbidity, mortality, and healthcare costs. Nurse-led interventions have been shown to be effective in reducing CLABSIs, but there is a need for further evaluation of these interventions to determine their effectiveness and impact on patient outcomes. This thesis aims to evaluate nurse-led interventions to reduce CLABSIs and contribute to the body of knowledge on infection prevention in healthcare settings.

Chapter 1 provides an introduction to the study, including background information, the problem statement, objectives, limitations, scope, significance, structure of the thesis, and definition of terms. Chapter 2 presents a comprehensive review of the literature on CLABSIs, nurse-led interventions, effectiveness, implementation strategies, barriers, patient outcomes, and cost-effectiveness. Chapter 3 describes the research methodology, including the design, population and sample, data collection methods, analysis, ethical considerations, validity, reliability, pilot study, and limitations.

Chapter 4 discusses the findings of the study, including comparisons of nurse-led interventions, factors influencing effectiveness, implications for practice, recommendations for future research, strengths, and limitations. Chapter 5 presents the conclusion and summary of key findings, implications for nursing practice, contribution to the field, limitations, recommendations for future research, and conclusion of the thesis on Evaluation of nurse-led interventions to reduce central line-associated bloodstream infections.

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