Drug repurposing for rare neurological disorders – Complete Phd and Masters Thesis

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Introduction

Drug repurposing has gained significant attention in recent years as a cost-effective and time-efficient strategy for identifying new uses for existing drugs. This approach has shown promising results in the treatment of various diseases, including rare neurological disorders. Rare neurological disorders are a group of conditions that affect a small percentage of the population and often lack effective treatment options due to limited research and funding. Therefore, repurposing existing drugs for these disorders presents a unique opportunity to address unmet medical needs and improve patient outcomes.

Chapter 1: Introduction
1.1 Introduction
1.2 Background of study
1.3 Problem Statement
1.4 Objective of study
1.5 Limitation of study
1.6 Scope of study
1.7 Significance of study
1.8 Structure of the Thesis
1.9 Definition of terms

Chapter 2: Literature Review
2.1 Overview of drug repurposing
2.2 Rare neurological disorders
2.3 Current treatment options
2.4 Challenges in drug development for rare diseases
2.5 Examples of successful drug repurposing for rare neurological disorders
2.6 Mechanisms of action in drug repurposing
2.7 Regulatory considerations in drug repurposing
2.8 Ethical considerations in drug repurposing
2.9 Future directions in drug repurposing research
2.10 Conclusion

Chapter 3: Research Methodology
3.1 Research design
3.2 Data collection methods
3.3 Study population
3.4 Inclusion and exclusion criteria
3.5 Data analysis techniques
3.6 Ethical considerations
3.7 Pilot study
3.8 Limitations
3.9 Validity and reliability
3.10 Conclusion

Chapter 4: Discussion of Findings
4.1 Analysis of data
4.2 Comparison with existing literature
4.3 Implications of findings
4.4 Recommendations for future research
4.5 Strengths and limitations of the study
4.6 Theoretical and practical implications
4.7 Conclusion

Chapter 5: Conclusion and Summary
5.1 Summary of findings
5.2 Contributions to the field
5.3 Implications for clinical practice
5.4 Limitations of the study
5.5 Recommendations for further research
5.6 Conclusion

Thesis Overview on Drug Repurposing for Rare Neurological Disorders

Drug repurposing, also known as drug repositioning or drug reprofiling, is a strategy that involves identifying new therapeutic uses for existing drugs. This approach has gained popularity in recent years as a cost-effective and time-efficient way to accelerate drug development and provide novel treatment options for a variety of diseases, including rare neurological disorders. These disorders affect a small percentage of the population and often present unique challenges in terms of diagnosis, treatment, and research.

The introduction chapter of this thesis provides an overview of drug repurposing for rare neurological disorders, outlining the background of the study, the problem statement, objectives, limitations, scope, significance, and structure of the thesis. The literature review chapter delves into the current state of drug repurposing research, the landscape of rare neurological disorders, treatment options, challenges in drug development, successful examples of drug repurposing, mechanisms of action, regulatory and ethical considerations, and future directions for research.

The research methodology chapter outlines the research design, data collection methods, study population, inclusion and exclusion criteria, data analysis techniques, ethical considerations, pilot study, limitations, validity and reliability. The discussion of findings chapter presents an analysis of the data, comparisons with existing literature, implications of the findings, recommendations for future research, strengths and limitations of the study, and theoretical and practical implications. The conclusion and summary chapter provides a summary of the findings, contributions to the field, implications for clinical practice, limitations of the study, recommendations for further research, and a conclusion on drug repurposing for rare neurological disorders.

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