Drug repurposing for pediatric disorders – Complete Phd and Masters Thesis

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Introduction

Drug repurposing, also known as drug repositioning or drug reprofiling, is the process of discovering new therapeutic uses for existing drugs that are already approved for other indications. This approach offers several advantages over traditional drug discovery methods, including reduced costs, shorter development timelines, and the potential for improved safety profiles. In recent years, drug repurposing has gained significant attention as a promising strategy for the treatment of pediatric disorders, which are often underserved by the pharmaceutical industry.

This thesis explores the potential of drug repurposing for pediatric disorders, focusing on the identification of existing drugs that may be repurposed for the treatment of various childhood conditions. The study aims to provide insights into the challenges and opportunities in drug repurposing for pediatric disorders, and to propose strategies for enhancing the efficiency and effectiveness of this approach in pediatric drug development.

Chapter 1: Introduction
1.1 Introduction
1.2 Background of study
1.3 Problem Statement
1.4 Objective of study
1.5 Limitation of study
1.6 Scope of study
1.7 Significance of study
1.8 Structure of the Thesis
1.9 Definition of terms

Chapter 2: Literature Review
2.1 Overview of drug repurposing
2.2 Drug repurposing in pediatric disorders
2.3 Challenges in pediatric drug development
2.4 Strategies for identifying repurposable drugs
2.5 Examples of successful drug repurposing
2.6 Regulatory considerations in pediatric drug repurposing
2.7 Ethical considerations in pediatric drug repurposing
2.8 Economic considerations in pediatric drug repurposing
2.9 Future directions in drug repurposing for pediatric disorders
2.10 Conclusion

Chapter 3: Research Methodology
3.1 Research design
3.2 Data collection methods
3.3 Data analysis procedures
3.4 Sample selection criteria
3.5 Ethical considerations
3.6 Instrumentation
3.7 Validity and reliability
3.8 Limitations of the study

Chapter 4: Discussion of Findings
4.1 Overview of findings
4.2 Identification of repurposable drugs for pediatric disorders
4.3 Comparative analysis of repurposing strategies
4.4 Implications for pediatric drug development
4.5 Recommendations for future research
4.6 Limitations of the study

Chapter 5: Conclusion and Summary
5.1 Summary of findings
5.2 Conclusions
5.3 Contributions to the field
5.4 Recommendations for practice
5.5 Areas for future research

Thesis Overview on Drug Repurposing for Pediatric Disorders

Drug repurposing is a promising approach for the treatment of pediatric disorders, offering a cost-effective and efficient way to identify new therapeutic options for children with unmet medical needs. This thesis explores the potential of drug repurposing in pediatric drug development, focusing on the challenges and opportunities in this field.

The literature review provides an overview of drug repurposing, highlighting the key concepts and principles underlying this approach. It also discusses the current state of drug repurposing in pediatric disorders, including the challenges and opportunities in this area. Examples of successful drug repurposing efforts in pediatric conditions are also presented, along with regulatory, ethical, and economic considerations.

The research methodology section outlines the design and procedures used in this study, including data collection methods, analysis procedures, and sample selection criteria. Ethical considerations and limitations of the study are also discussed.

The discussion of findings chapter presents the results of the study, including the identification of repurposable drugs for pediatric disorders and a comparative analysis of repurposing strategies. The implications of these findings for pediatric drug development are discussed, along with recommendations for future research.

In conclusion, this thesis contributes to the growing body of literature on drug repurposing for pediatric disorders, providing insights into the challenges and opportunities in this field. Recommendations for practice and future research directions are also provided, with the aim of advancing the development of new therapeutic options for children with medical conditions.

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