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Introduction:

In recent years, RNA therapeutics have emerged as a promising approach for the treatment of various diseases, including cancer, genetic disorders, and infectious diseases. However, one of the main challenges in the development of RNA therapeutics is the efficient delivery of these molecules to their target cells. Drug delivery systems play a crucial role in overcoming the barriers associated with the delivery of RNA therapeutics, such as stability, cellular uptake, and intracellular trafficking.

This thesis aims to provide a comprehensive overview of drug delivery systems for RNA therapeutics, focusing on the different strategies and technologies that have been developed to improve the delivery of RNA molecules to target cells. The thesis will also discuss the challenges and opportunities in this field, as well as the future directions for the development of novel drug delivery systems for RNA therapeutics.

Chapter One: Introduction
1.1 Introduction
1.2 Background of study
1.3 Problem Statement
1.4 Objective of study
1.5 Limitation of study
1.6 Scope of study
1.7 Significance of study
1.8 Structure of the Thesis
1.9 Definition of terms

Chapter Two: Literature Review
2.1 Overview of RNA therapeutics
2.2 Types of RNA therapeutics
2.3 Challenges in RNA delivery
2.4 Strategies for RNA delivery
2.5 Lipid-based delivery systems
2.6 Polymer-based delivery systems
2.7 Peptide-based delivery systems
2.8 Inorganic nanoparticle-based delivery systems
2.9 Exosomes as delivery vehicles for RNA therapeutics
2.10 Clinical applications of RNA therapeutics

Chapter Three: Research Methodology
3.1 Research design
3.2 Data collection methods
3.3 Data analysis techniques
3.4 Sample selection
3.5 Ethical considerations
3.6 Validation of results
3.7 Statistical analysis
3.8 Research limitations

Chapter Four: Discussion of Findings
4.1 Efficiency of different delivery systems for RNA therapeutics
4.2 Cellular uptake and intracellular trafficking of RNA molecules
4.3 Stability of RNA molecules in delivery systems
4.4 Toxicity and immunogenicity of delivery systems
4.5 Future directions for the development of RNA delivery systems

Chapter Five: Conclusion and Summary
5.1 Summary of key findings
5.2 Implications of the study
5.3 Recommendations for future research
5.4 Conclusion

Thesis Overview:

The development of drug delivery systems for RNA therapeutics is a rapidly evolving field with great potential for the treatment of various diseases. This thesis provides a comprehensive overview of the different strategies and technologies that have been developed to improve the delivery of RNA molecules to target cells. The literature review highlights the challenges and opportunities in this field, as well as the clinical applications of RNA therapeutics. The research methodology chapter outlines the design and methods used in the study, while the discussion of findings chapter presents the efficiency, stability, and toxicity considerations of different delivery systems. The conclusion and summary chapter summarizes the key findings of the study and provides recommendations for future research in the field of drug delivery systems for RNA therapeutics.

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