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Introduction

Hypertension, also known as high blood pressure, is a common yet serious medical condition that affects millions of people worldwide. It is a major risk factor for cardiovascular diseases such as heart attacks, strokes, and kidney failure. Despite the availability of various antihypertensive medications, many patients still struggle to control their blood pressure effectively due to factors such as medication side effects, drug resistance, and poor adherence to treatment.

The development of novel antihypertensive medications is crucial in addressing these challenges and improving patient outcomes. This thesis aims to explore the current landscape of antihypertensive medications, identify gaps in existing treatments, and propose new strategies for the development of more effective and tolerable drugs for hypertension.

Chapter 1: Introduction
1.1 Introduction
1.2 Background of study
1.3 Problem Statement
1.4 Objective of study
1.5 Limitation of study
1.6 Scope of study
1.7 Significance of study
1.8 Structure of the Thesis
1.9 Definition of terms

Chapter 2: Literature Review
2.1 Overview of hypertension
2.2 Current treatment options for hypertension
2.3 Challenges in managing hypertension
2.4 Emerging trends in antihypertensive drug development
2.5 Mechanisms of action of novel antihypertensive medications
2.6 Clinical trials of novel antihypertensive medications
2.7 Side effects and safety profiles of novel antihypertensive medications
2.8 Drug interactions and contraindications
2.9 Patient perspectives on antihypertensive medication use
2.10 Future directions in antihypertensive drug research

Chapter 3: Research Methodology
3.1 Research design
3.2 Study population
3.3 Data collection methods
3.4 Data analysis techniques
3.5 Ethical considerations
3.6 Pilot study
3.7 Sample size calculation
3.8 Data validation

Chapter 4: Discussion of Findings
4.1 Efficacy of novel antihypertensive medications
4.2 Safety and tolerability of novel antihypertensive medications
4.3 Factors influencing patient adherence to antihypertensive treatment
4.4 Comparison of novel antihypertensive medications with existing treatments
4.5 Implications for clinical practice
4.6 Recommendations for future research
4.7 Limitations of the study
4.8 Strengths of the study

Chapter 5: Conclusion and Summary
5.1 Summary of key findings
5.2 Implications for practice
5.3 Recommendations for policy makers
5.4 Contributions to the field
5.5 Future research directions

Overall, this thesis will provide valuable insights into the development of novel antihypertensive medications and contribute to the advancement of hypertension management. By addressing the limitations of current treatments and exploring new possibilities for drug development, this research aims to improve the quality of care for hypertensive patients and reduce the burden of cardiovascular diseases globally.

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