Development of drugs targeting protein-protein interactions – Complete Phd and Masters Thesis

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Introduction

The field of drug discovery and development has continuously evolved over the years, with researchers constantly exploring new strategies to target various biological processes. One such area of interest is the development of drugs that target protein-protein interactions (PPIs). PPIs play a crucial role in numerous cellular processes, and their dysregulation has been implicated in various diseases, including cancer, neurodegenerative disorders, and infectious diseases. Thus, targeting PPIs presents a promising approach for the development of novel therapeutics.

This thesis aims to provide an in-depth analysis of the development of drugs targeting PPIs. The following chapters will explore the background of study, problem statement, objectives, limitations, scope, significance, and structure of the thesis. Additionally, key terms related to the topic will be defined to enhance understanding.

Chapter 1: Introduction
1.1 Introduction
1.2 Background of Study
1.3 Problem Statement
1.4 Objective of Study
1.5 Limitation of Study
1.6 Scope of Study
1.7 Significance of Study
1.8 Structure of the Thesis
1.9 Definition of Terms

Chapter 2: Literature Review
2.1 Overview of Protein-Protein Interactions
2.2 Importance of Targeting PPIs in Drug Development
2.3 Strategies for Targeting PPIs
2.4 Challenges in Developing Drugs Targeting PPIs
2.5 Case Studies of Successful PPI Targeted Drugs
2.6 Computational Approaches in PPI Drug Discovery
2.7 Recent Advances in PPI Targeted Drug Development
2.8 Future Directions in the Field
2.9 Summary of Literature Review

Chapter 3: Research Methodology
3.1 Research Design
3.2 Data Collection Methods
3.3 Data Analysis Techniques
3.4 Study Population
3.5 Sampling Techniques
3.6 Experimental Procedures
3.7 In vitro and in vivo Studies
3.8 Ethical Considerations

Chapter 4: Discussion of Findings
4.1 Analysis of Research Results
4.2 Comparison with Existing Literature
4.3 Implications of Findings
4.4 Limitations of the Study
4.5 Future Research Directions
4.6 Conclusion

Chapter 5: Conclusion and Summary
5.1 Summary of Key Findings
5.2 Implications of the Study
5.3 Contributions to the Field
5.4 Recommendations for Future Research
5.5 Conclusion

Overall, this thesis will provide valuable insights into the development of drugs targeting PPIs and contribute to the advancement of drug discovery in this exciting field.

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