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Table of Contents:

Chapter 1: Introduction
1.1 Background of the Study
1.2 Problem Statement
1.3 Research Questions
1.4 Objectives of the Study
1.5 Significance of the Study
1.6 Limitations of the Study
1.7 Scope of the Study

Chapter 2: Literature Review
2.1 Introduction to RNA-based therapeutics
2.2 Liver diseases and current treatment options
2.3 RNA-based therapeutics for liver diseases
2.4 Challenges and limitations of RNA-based therapeutics
2.5 Recent advancements in the field

Chapter 3: Research Methodology
3.1 Research Design
3.2 Data Collection Methods
3.3 Data Analysis Techniques
3.4 Sampling Strategy
3.5 Ethical Considerations

Chapter 4: Discussion of Findings
4.1 Overview of the Findings
4.2 Comparison of Findings with Existing Literature
4.3 Implications of Findings for RNA-based therapeutics for liver diseases
4.4 Recommendations for Future Research

Chapter 5: Conclusion and Summary
5.1 Summary of Key Findings
5.2 Conclusion
5.3 Contributions to the Field
5.4 Limitations of the Study
5.5 Recommendations for Practitioners and Policy Makers

Overview:

Developing RNA-based therapeutics for liver diseases is a rapidly evolving field that holds great promise for the treatment of various liver disorders. Liver diseases such as fatty liver disease, viral hepatitis, and liver cancer pose significant health challenges worldwide, and current treatment options are often limited in their efficacy. RNA-based therapeutics, including mRNA, siRNA, and antisense oligonucleotides, offer a novel approach to treating liver diseases by targeting specific genes or pathways involved in disease progression.

This brief overview will explore the current landscape of RNA-based therapeutics for liver diseases, including an overview of the different types of RNA molecules used in therapy, their mechanisms of action, and the challenges associated with their development and delivery. It will also discuss recent advancements in the field, such as the development of lipid nanoparticles for improved delivery of RNA therapeutics to target cells in the liver.

Additionally, this overview will provide a summary of the key findings from the literature review, research methodology, and discussion of findings chapters in the PhD thesis. The study aims to contribute to the growing body of knowledge on RNA-based therapeutics for liver diseases and provide recommendations for future research and clinical practice in this exciting and innovative field.

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