Design and development of a microfluidic device for drug delivery – Complete Phd and Masters Thesis

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Introduction

Drug delivery plays a crucial role in the field of medicine as it determines the effectiveness of treatment for various diseases. Over the years, advancements in technology have led to the development of novel drug delivery systems to improve drug efficacy and reduce side effects. One such emerging technology is microfluidics, which involves the manipulation of small volumes of fluids on the microscale level. The precise control and manipulation of fluids in microfluidic devices have shown great potential for drug delivery applications. In this thesis, we aim to design and develop a microfluidic device for drug delivery, with a focus on improving drug targeting and release kinetics.

Chapter 1: Introduction
1.1 Introduction
1.2 Background of study
1.3 Problem Statement
1.4 Objective of study
1.5 Limitation of study
1.6 Scope of study
1.7 Significance of study
1.8 Structure of the Thesis
1.9 Definition of terms

Chapter 2: Literature Review
2.1 Introduction to microfluidics
2.2 Drug delivery systems
2.3 Microfluidic devices for drug delivery
2.4 Advantages and challenges of microfluidic drug delivery
2.5 Current trends in microfluidic drug delivery
2.6 Recent developments in microfluidic drug delivery
2.7 Applications of microfluidic drug delivery
2.8 Regulatory considerations for microfluidic drug delivery
2.9 Future prospects of microfluidic drug delivery
2.10 Gaps in current research on microfluidic drug delivery

Chapter 3: Research Methodology
3.1 Research design
3.2 Materials and methods
3.3 Fabrication of microfluidic device
3.4 Characterization of microfluidic device
3.5 Drug loading and release studies
3.6 Computational modeling of drug transport
3.7 In vitro and in vivo studies
3.8 Data analysis and interpretation

Chapter 4: Discussion of Findings
4.1 Fabrication and characterization of microfluidic device
4.2 Drug loading and release kinetics
4.3 Computational modeling results
4.4 In vitro and in vivo studies
4.5 Comparison with existing drug delivery systems
4.6 Optimization strategies
4.7 Limitations and challenges
4.8 Future directions for research
4.9 Implications of findings

Chapter 5: Conclusion and Summary
5.1 Summary of findings
5.2 Contribution to knowledge
5.3 Practical implications
5.4 Recommendations for future research
5.5 Conclusion

Thesis Overview

The design and development of a microfluidic device for drug delivery is a significant research undertaking that aims to revolutionize drug delivery systems. This thesis explores the potential of microfluidics in enhancing drug targeting and release kinetics to improve treatment outcomes. The literature review provides a comprehensive overview of microfluidic drug delivery systems, highlighting their advantages, challenges, and current trends. The research methodology details the experimental approach, including the fabrication, characterization, and testing of the microfluidic device for drug delivery. The discussion of findings presents the results of the experiments, along with their implications and future directions for research. The conclusion summarizes the key findings and contributions of the study, offering recommendations for further investigation in this field. Overall, this thesis aims to advance the field of drug delivery through the innovative use of microfluidic technology.

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